{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:48:43Z","timestamp":1777693723232,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:p>Invasive pneumococcal meningitis is a life-threatening infectious disease affecting the central nervous system. It continues to be the most common type of community-acquired acute bacterial meningitides. Despite advances in neuro-critical care, the case fatality rate remains high. Rapid diagnosis and initiation of antibiotic therapy precludes mortality and long-term neurological sequelae in survivors. However, not all cases are easily recognised, and unanticipated complications may impede optimal course and outcome. Here, we describe a case of invasive pneumococcal meningoencephalitis in a 65-year-old man with an unusual initial presentation and pitfalls in the course of the disease. We highlight the importance of early diagnosis and treatment as well as recognition and management of complications.<\/jats:p>","DOI":"10.1177\/1179547617725505","type":"journal-article","created":{"date-parts":[[2017,8,16]],"date-time":"2017-08-16T03:02:14Z","timestamp":1502852534000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pitfalls in the Diagnosis and Management of Invasive Pneumococcal Meningoencephalitis \u2013 What We Can Learn From a Case"],"prefix":"10.1177","volume":"10","author":[{"given":"Pascale S","family":"Grzonka","sequence":"first","affiliation":[{"name":"Medical Intensive Care Units, University Hospital Basel, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raoul","family":"Sutter","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Units, University Hospital Basel, Basel, Switzerland"},{"name":"University of Basel, Basel, Switzerland"},{"name":"Division of Clinical Neurophysiology, Department of Neurology, University Hospital Basel, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,8,16]]},"reference":[{"key":"bibr1-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040845"},{"key":"bibr2-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70805-9"},{"key":"bibr3-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000239434.26669.65"},{"key":"bibr4-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-016-1498-8"},{"key":"bibr5-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70048-7"},{"key":"bibr6-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70288-X"},{"key":"bibr7-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-321"},{"key":"bibr8-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00430-2"},{"key":"bibr9-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1086\/340979"},{"key":"bibr10-1179547617725505","volume":"6","author":"Brouwer MC","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr11-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002023"},{"key":"bibr12-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000288178.91614.5d"},{"key":"bibr13-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.45"},{"key":"bibr14-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2011.05.018"},{"key":"bibr15-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2010.02888.x"},{"key":"bibr16-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318275882f"},{"key":"bibr17-1179547617725505","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-014-0070-0"}],"container-title":["Clinical Medicine Insights: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1179547617725505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1179547617725505","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1179547617725505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:13:29Z","timestamp":1777454009000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1179547617725505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,1]]},"references-count":17,"alternative-id":["10.1177\/1179547617725505"],"URL":"https:\/\/doi.org\/10.1177\/1179547617725505","relation":{},"ISSN":["1179-5476","1179-5476"],"issn-type":[{"value":"1179-5476","type":"print"},{"value":"1179-5476","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,1]]},"article-number":"1179547617725505"}}