{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:52:14Z","timestamp":1777693934484,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Cutaneous vasculitis occurs in a sizable minority of patients with Sjogren syndrome. In addition, their response to different modalities of therapy is variable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Description:<\/jats:title>\n                    <jats:p>We present a case of a 66-year-old female with Sjogren syndrome cutaneous vasculitis in whom combination treatment with Rituximab and Azathioprine failed to show a favorable response. However, methotrexate proved to be an excellent alternative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>In cutaneous vasculitis, in addition to the necessary local therapy applied to the affected limbs, methotrexate produced a complete response when other treatment modalities failed. Therefore, it may be advisable to use methotrexate to treat cutaneous vasculitis before trying Rituximab.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In cutaneous vasculitis associated with Sjogren syndrome, methotrexate can be an early effective therapeutic strategy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795476221088489","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T08:12:29Z","timestamp":1647850349000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Livedoid Vasculitis in a Patient With Sjogren Syndrome Successfully Treated With Methotrexate"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8616-1205","authenticated-orcid":false,"given":"Abdulkarim Yousef","family":"Aldehaim","sequence":"first","affiliation":[{"name":"Unit of Rheumatology, Department of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdurhman Saud","family":"Alarfaj","sequence":"additional","affiliation":[{"name":"Unit of Rheumatology, Department of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,21]]},"reference":[{"key":"bibr1-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e3181b76ab5"},{"key":"bibr2-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.041186"},{"key":"bibr3-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-009-8152-z"},{"key":"bibr4-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-011-0207-5"},{"key":"bibr5-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200207000-00003"},{"key":"bibr6-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.02.020"},{"key":"bibr7-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2017.04.011"},{"key":"bibr8-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22968"},{"key":"bibr9-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket427"},{"key":"bibr10-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2020.07.013"},{"key":"bibr11-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2018.04.012"},{"key":"bibr12-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02898.x"},{"key":"bibr13-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(96)00405-6"},{"key":"bibr14-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198707000-00012"},{"key":"bibr15-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70039-8"},{"key":"bibr16-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.04510010083008"},{"key":"bibr17-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202293"},{"key":"bibr18-11795476221088489","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-200086"}],"container-title":["Clinical Medicine Insights: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476221088489","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795476221088489","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476221088489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:14:04Z","timestamp":1777454044000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795476221088489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":18,"alternative-id":["10.1177\/11795476221088489"],"URL":"https:\/\/doi.org\/10.1177\/11795476221088489","relation":{},"ISSN":["1179-5476","1179-5476"],"issn-type":[{"value":"1179-5476","type":"print"},{"value":"1179-5476","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"11795476221088489"}}