{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T13:07:14Z","timestamp":1784293634236,"version":"3.55.0"},"reference-count":36,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Diazoxide is one of the FDA-approved pharmacologic treatments for hyperinsulinemic hypoglycemia, however, its adverse effects in infants are not well described. We reported a 37-week-old boy with the diagnosis of hypoglycemia. We started a dextrose infusion, but we used oral diazoxide, due to hypoglycemia episodes despite the increase in dextrose intake. The newborn had a normoglycemic condition after gradually increasing the diazoxide dose to 15\u2009mg\/kg\/day. He was fully breastfed and discharged at 14\u2009days of age with ongoing diazoxide. In weekly serial clinical follow-ups, the parents noticed an increase in the growth of forehead and facial hair that was diagnosed as diazoxide-induced hypertrichosis. Diazoxide was gradually tapered, and hypertrichosis continued until 1\u2009month after dioxide discontinuation. Diazoxide use in NICU settings has increased over time. Diazoxide has many side effects, one of which is hypertrichosis. Many diazoxide side effects have been reported in adults or children and few studies have reported the prevalence of these adverse effects of diazoxide in neonates and infants.<\/jats:p>","DOI":"10.1177\/11795476231151330","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T01:13:47Z","timestamp":1674782027000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Diazoxide-Induced Hypertrichosis in a Neonate With Transient Hyperinsulinism"],"prefix":"10.1177","volume":"16","author":[{"given":"Seyyed Javad","family":"Boskabadi","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sima","family":"Ramezaninejad","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoumeh","family":"Sohrab","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roya","family":"Farhadi","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Pediatrics Infectious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,26]]},"reference":[{"key":"bibr1-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31737"},{"key":"bibr2-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-95672-5_10"},{"key":"bibr3-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.13186"},{"key":"bibr4-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1252746"},{"key":"bibr5-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1016\/j.epsc.2020.101731"},{"key":"bibr6-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0b013e328334f061"},{"key":"bibr7-11795476231151330","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0218-4"},{"key":"bibr8-11795476231151330","volume-title":"Hypoglycemia - 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