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Stroke in ASD may be due to paradoxical emboli from the right heart or a left ventricular thrombus which develops as a result of atrial fibrillation, a common arrhythmia in ASD. We present a case of a 32-year-old Ghanaian man with history of ASD who presented with progressive memory loss with magnetic resonance imaging scan of the brain showing multiple infarcts, microvascular disease, and cerebral atrophy.<\/jats:p>","DOI":"10.1177\/11795476231176713","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T02:41:02Z","timestamp":1685068862000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Progressive Memory Decline in a Patient With Atrial Septal Defect: Case Report and Literature Review"],"prefix":"10.1177","volume":"16","author":[{"given":"Yaw Amo","family":"Wiafe","sequence":"first","affiliation":[{"name":"Department of Medical Diagnostics, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0549-6290","authenticated-orcid":false,"given":"Gordon Manu","family":"Amponsah","sequence":"additional","affiliation":[{"name":"Department of Physiology, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6043-0289","authenticated-orcid":false,"given":"George","family":"Asafu Adjaye Frimpong","sequence":"additional","affiliation":[{"name":"Department of Radiology, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8934-8542","authenticated-orcid":false,"given":"Isaac Kofi","family":"Owusu","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"bibr1-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2012-301682"},{"key":"bibr2-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00101.2003"},{"key":"bibr3-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-7-55"},{"key":"bibr4-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617704101082"},{"key":"bibr5-11795476231176713","first-page":"135","volume":"5","author":"Justin BN","year":"2013","journal-title":"Clin Epidemiol"},{"key":"bibr6-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12242"},{"key":"bibr7-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.10.025"},{"key":"bibr8-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.8.883"},{"key":"bibr9-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.015843"},{"key":"bibr10-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2015.12.004"},{"key":"bibr11-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2019.06.030"},{"key":"bibr12-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.866319"},{"key":"bibr13-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.031573"},{"key":"bibr14-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.10.077"},{"key":"bibr15-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.008396"},{"key":"bibr16-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951116001396"},{"key":"bibr17-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1017\/S104795111700138X"},{"key":"bibr18-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.025"},{"key":"bibr19-11795476231176713","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.946343"},{"key":"bibr20-11795476231176713","unstructured":"BMJ Best Practice US. 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