{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:59:42Z","timestamp":1792738782383,"version":"4.5.0"},"reference-count":83,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Infertility affects 15% of couples in reproductive age worldwide. In women in particular, infertility can be caused by various abnormalities, with polycystic ovary syndrome (PCOS) being the most common. Currently, there are many assisted reproductive techniques (ART) available to combat the burden of infertility. However, positive results are not guaranteed. The administration of inositol has been shown to increase positive reproductive outcomes in women undergoing ART. Here we present a series of clinical cases in which women with a history of infertility and previously failed ART, supplemented with a specific 3.6:1 MYO:DCI ratio, antioxidants, vitamins, and minerals for a period of 1 to 3 months before undergoing in vitro fertilization (IVF). In this series of case reports, we provide preliminary evidence that supplementation with a specific 3.6:1 MYO to DCI ratio, as well as antioxidants, vitamins, and minerals may contribute positively to female fertility in women undergoing IVF, with a history of primary or secondary infertility and previously failed ART.<\/jats:p>","DOI":"10.1177\/11795476241242265","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T22:53:45Z","timestamp":1711752825000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Treatment With a Patented 3.6:1 Myo-Inositol to D-chiro-Inositol Ratio, Antioxidants, Vitamins and Minerals Food Supplement in Women With a History of Assisted Reproductive Technique (ART) Failures: A Series of Case Reports"],"prefix":"10.1177","volume":"17","author":[{"given":"A.","family":"Armijo-S\u00e1nchez","sequence":"first","affiliation":[{"name":"Hospital Universitario de Valme, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Ben\u00edtez Castillo","sequence":"additional","affiliation":[{"name":"Hospital Universitario Materno Infantil de Canarias, Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Garc\u00eda-Vidal","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Valme, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Luna Chadid","sequence":"additional","affiliation":[{"name":"ARPA MEDICA, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Salvador Ballada","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario San Mill\u00e1n- San Pedro, Logro\u00f1o, La Rioja, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Valls Ricart","sequence":"additional","affiliation":[{"name":"Instituto de Reproducci\u00f3n CEFER, Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Torres Pellens","sequence":"additional","affiliation":[{"name":"Tufts Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,29]]},"reference":[{"key":"bibr1-11795476241242265","unstructured":"World Health Organization. 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