{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:57:59Z","timestamp":1777694279808,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Uterine fibroids are common benign smooth muscle tumours that may complicate pregnancy with pain and pressure symptoms. While conservative management is preferred due to the risk of haemorrhage and pregnancy loss, antepartum myomectomy may be indicated in selected cases with intractable symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We report 2 cases of successful antepartum myomectomy performed in the second trimester for severe, unrelenting pain secondary to large fibroids. The first case involved a 27-year-old primigravida at 15\u2009+\u20092\u2009weeks\u2019 gestation with a 22\u2009\u00d7\u200916\u2009\u00d7\u200917\u2009cm pedunculated fibroid causing respiratory compromise. The second case involved a 41-year-old multigravida at 14\u2009weeks\u2019 gestation with multiple fibroids, the largest measuring 19\u2009\u00d7\u200921\u2009cm. Both patients underwent open myomectomy following multidisciplinary evaluation and counselling. Estimated blood loss was minimal, and postoperative recovery was uneventful. Pregnancies progressed to term, resulting in favourable maternal and fotal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Antepartum myomectomy, though rarely indicated, can be safely performed in well-counselled, carefully selected patients with severe symptoms and favourable fibroid characteristics. Preoperative imaging, multidisciplinary planning and meticulous surgical technique are crucial for optimal outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795476251407360","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T06:03:19Z","timestamp":1766383399000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Myomectomy During Pregnancy: Decision-Making and Outcomes\u2014A Report of 2 Cases"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0180-0432","authenticated-orcid":false,"given":"Gerald Tochukwu","family":"Igwemadu","sequence":"first","affiliation":[{"name":"Barking, Havering and Redbridge University NHS Trust, Romford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akobundu","family":"Nnochiri","sequence":"additional","affiliation":[{"name":"Barking, Havering and Redbridge University NHS Trust, Romford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Sharma","sequence":"additional","affiliation":[{"name":"Barking, Havering and Redbridge University NHS Trust, Romford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gat083"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/tog.12491"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318197bbaf"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.03.066"},{"key":"e_1_3_3_6_2","unstructured":"Ouyang DW Norwitz ER. Uterine fibroids (leiomyomas): issues in pregnancy. UpToDate. 2024. Accessed August 2024. https:\/\/www.uptodate.com\/contents\/uterine-fibroids-leiomyomas-issues-in-pregnancy"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-999317"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12399"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjae.2022.12.001"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.08.018"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.13816"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.893382"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/gyn.2022.0127"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.4274\/jtgga.galenos.2018.2018.0148"}],"container-title":["Clinical Medicine Insights: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476251407360","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795476251407360","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476251407360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:14:49Z","timestamp":1777454089000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795476251407360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":13,"alternative-id":["10.1177\/11795476251407360"],"URL":"https:\/\/doi.org\/10.1177\/11795476251407360","relation":{},"ISSN":["1179-5476","1179-5476"],"issn-type":[{"value":"1179-5476","type":"print"},{"value":"1179-5476","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"article-number":"11795476251407360"}}