{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:55:21Z","timestamp":1777694121031,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Tuberculosis (TB) remains a leading infectious disease worldwide, with Ethiopia among the highest-burden countries. Laryngeal tuberculosis is rare, accounting for less than 1%\u20132% of TB cases and typically affects the posterior glottis and true vocal cords. However, atypical involvement of the subglottic region is uncommon and can closely resemble laryngeal carcinoma both clinically and radiologically, posing a significant diagnostic challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We report a 64-year-old man with a 1-year history of progressive hoarseness. Neck CT demonstrated asymmetric mucosal thickening and enhancement of the glottis with anterior subglottic extension, along with a rim-enhancing necrotic prelaryngeal node which are findings highly suggestive of malignancy. Chest CT revealed right upper lobe cavitation, nodularity and tree-in-bud opacities consistent with active pulmonary tuberculosis. GeneXpert MTB\/RIF confirmed Mycobacterium tuberculosis, and laryngeal biopsy revealed caseating granulomatous inflammation with acid-fast bacilli. A diagnosis of concomitant pulmonary and laryngeal tuberculosis was established, and the patient was started on standard first-line anti-tubercular therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Laryngeal tuberculosis typically involves the posterior glottis, but in this case, anterior subglottic disease with necrotic nodal involvement created strong radiologic overlap with carcinoma. Recognition of such atypical patterns is crucial, especially in endemic regions, as misdiagnosis may lead to unnecessary surgical interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Persistent hoarseness with mass-like laryngeal lesions should prompt consideration of tuberculosis in endemic settings. Radiologists play a key role in identifying suggestive features and integrating them with pulmonary imaging and microbiologic results to ensure accurate diagnosis and timely treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795476261430039","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T09:49:01Z","timestamp":1774259341000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Hoarseness Beyond Cancer: Laryngeal Presentation of Tuberculosis"],"prefix":"10.1177","volume":"19","author":[{"given":"Leul Adane","family":"Chemeda","sequence":"first","affiliation":[{"name":"Department of Radiology, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yewibdar Mulu","family":"Mekonnen","sequence":"additional","affiliation":[{"name":"Department of Radiology, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5136-5999","authenticated-orcid":false,"given":"Helina K.","family":"Teklehaimanot","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"6543595","article-title":"Primary tuberculosis of buccal and labial mucosa: literature review and a rare case report of a Public Health Menace","volume":"2023","author":"Sriram S","year":"2023","unstructured":"Sriram S, Hasan S, Saeed S, Ahmad SA, Panda S. Primary tuberculosis of buccal and labial mucosa: literature review and a rare case report of a Public Health Menace. Case Rep Dent. 2023;2023:6543595.","journal-title":"Case Rep Dent"},{"key":"e_1_3_3_3_2","unstructured":"WHO Global Lists of High Burden Countries for Tuberculosis (TB) TB\/HIV and Multidrug\/Rifampicin-Resistant TB (MDR\/RR-TB) 2021-2025: Background Document. 1st ed. World Health Organization; 2021."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2013.877157"},{"issue":"180","key":"e_1_3_3_5_2","first-page":"446","article-title":"A Textbook for Students and Practitioners. By Sir St. Clair Thomson, M.D., F.R.C.P., F.R.C.S. Revised by V. E. Negus, D.Sc., M.S., F.R.C.S., Consulting Surgeon for Diseases of the Ear, Nose, and Throat, King\u2019s College Hospital; with the assistance of G. H. Bateman, M.A., B.M., B.Ch., F.R.C.S., Surgeon to the Ear, Nose, and Throat Department, St. Thomas\u2019s Hospital, London. Sixth edition. 9 1\/8 \u00d7 6 1\/8 in. Pp. 1040 + xvi, with 46 Plates, some coloured, and 353 illustrations","volume":"43","author":"Diseases of the nose and throat","year":"1955","unstructured":"Diseases of the nose and throat. A Textbook for Students and Practitioners. By Sir St. Clair Thomson, M.D., F.R.C.P., F.R.C.S. Revised by V. E. Negus, D.Sc., M.S., F.R.C.S., Consulting Surgeon for Diseases of the Ear, Nose, and Throat, King\u2019s College Hospital; with the assistance of G. H. Bateman, M.A., B.M., B.Ch., F.R.C.S., Surgeon to the Ear, Nose, and Throat Department, St. Thomas\u2019s Hospital, London. Sixth edition. 9 1\/8 \u00d7 6 1\/8 in. Pp. 1040 + xvi, with 46 Plates, some coloured, and 353 illustrations. 1955. London: Cassell & Co. Ltd. 90s. Br J Surg. 1956;43(180):446-447.","journal-title":"Br J Surg"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2009.09.004"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023770"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198408000-00019"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-248095"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60443-1"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-018-0970-y"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200011000-00034"},{"key":"e_1_3_3_13_2","unstructured":"Unal M Vayisoglu Y Guner N Karabacak T. Tuberculosis of the aryepiglottic fold and sinus pyriformis: a rare entity. Mt Sinai J Med. 2006;73(5):806-809. Accessed September 25 2025. https:\/\/pubmed.ncbi.nlm.nih.gov\/17008943\/"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.166.2.8553964"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.4103\/0971-3026.59745"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2018.19.5.859"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-2113.44221"}],"container-title":["Clinical Medicine Insights: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476261430039","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795476261430039","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476261430039","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:14:29Z","timestamp":1777454069000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795476261430039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":16,"alternative-id":["10.1177\/11795476261430039"],"URL":"https:\/\/doi.org\/10.1177\/11795476261430039","relation":{},"ISSN":["1179-5476","1179-5476"],"issn-type":[{"value":"1179-5476","type":"print"},{"value":"1179-5476","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"article-number":"11795476261430039"}}