{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:55:30Z","timestamp":1777694130255,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Fascioliasis is a neglected tropical disease caused by\n                      <jats:italic toggle=\"yes\">Fasciola species<\/jats:italic>\n                      that can present with nonspecific abdominal symptoms and mimic surgical emergencies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>\n                      We report a 12-year-old Ethiopian boy who presented with right-sided abdominal pain, fever, and marked eosinophilia and was initially suspected to have acute appendicitis. Diagnostic laparoscopy revealed hepatic rather than appendiceal pathology. Imaging demonstrated subcapsular hepatic tracks, and serologic testing confirmed\n                      <jats:italic toggle=\"yes\">Fasciola species<\/jats:italic>\n                      infection (most probably\n                      <jats:italic toggle=\"yes\">Fasciola gigantica<\/jats:italic>\n                      in the Ethiopian context). Histopathology showed eosinophil-rich granulomatous hepatitis with helminthic structures. The patient was treated with triclabendazole and recovered completely.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the importance of considering parasitic infections such as fascioliasis in children presenting with atypical acute abdominal pain in endemic regions. Early use of imaging and serologic testing may prevent unnecessary surgical interventions and allow timely curative therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795476261438872","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T09:13:26Z","timestamp":1776676406000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Hepatic Fascioliasis Masquerading as Acute Appendicitis in a Child: A Case Report"],"prefix":"10.1177","volume":"19","author":[{"given":"Bisrat Abate","family":"Bekele","sequence":"first","affiliation":[{"name":"School of Public Health, Washington University in St. Louis, Saint Louis, MO, USA"},{"name":"School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0556-4071","authenticated-orcid":false,"given":"Mikiyas G.","family":"Teferi","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muluken Bekele","family":"Wondimagegnehu","sequence":"additional","affiliation":[{"name":"Department of ENT, Hawassa University Comprehensive Specialized Hospital, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca Haile","family":"Tesfay","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alem Mekete","family":"Ayalew","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biniam Girma","family":"Tsega","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Myungsung Medical College\/MCM Comprehensive Specialized Hospital, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taye Jemberu","family":"Robele","sequence":"additional","affiliation":[{"name":"Department of Pathology, Myungsung Medical College\/MCM Comprehensive Specialized Hospital, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0261166"},{"issue":"4","key":"e_1_3_3_3_2","first-page":"208","article-title":"Prevalence of human and animal fasciolosis in Butajira and Gilgel Gibe health demographic surveillance system sites in Ethiopia","volume":"8","author":"Abaya SW","year":"2023","unstructured":"Abaya SW, Mereta ST, Tulu FD, et al. Prevalence of human and animal fasciolosis in Butajira and Gilgel Gibe health demographic surveillance system sites in Ethiopia. Trop Med Infect Dis. 2023;8(4):208.","journal-title":"Trop Med Infect Dis"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00088-19"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.5897\/JVMAH2014.0352"},{"issue":"5","key":"e_1_3_3_6_2","first-page":"635","article-title":"Small ruminant fasciolosis in Jimma area of southwestern Ethiopia: its epidemiology and minimum monetary loss","volume":"9","author":"Kedir S","year":"2012","unstructured":"Kedir S, Deressa B, Tigre W. Small ruminant fasciolosis in Jimma area of southwestern Ethiopia: its epidemiology and minimum monetary loss. Glob Vet. 2012;9(5):635-641.","journal-title":"Glob Vet"},{"issue":"5","key":"e_1_3_3_7_2","first-page":"123","article-title":"Emerging human fascioliasis in India: review of case reports, climate change impact, and geo-historical correlation defining areas and seasons of high infection risk","volume":"10","author":"Mas-Coma S","year":"2025","unstructured":"Mas-Coma S, Cuervo PF, Chetri PB, Tripathi T, Gabrielli AF, Bargues MD. Emerging human fascioliasis in India: review of case reports, climate change impact, and geo-historical correlation defining areas and seasons of high infection risk. Trop Med Infect Dis. 2025;10(5):123.","journal-title":"Trop Med Infect Dis"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2012.02964.x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaf116"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-021-02945-9"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182014000869"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trv110"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2024.e02045"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10189"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI34261"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trz093"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.14.12.1513"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed10080224"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2025.01.030"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijregi.2022.03.016"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11686-023-00726-6"}],"container-title":["Clinical Medicine Insights: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476261438872","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795476261438872","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476261438872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:14:31Z","timestamp":1777454071000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795476261438872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":20,"alternative-id":["10.1177\/11795476261438872"],"URL":"https:\/\/doi.org\/10.1177\/11795476261438872","relation":{},"ISSN":["1179-5476","1179-5476"],"issn-type":[{"value":"1179-5476","type":"print"},{"value":"1179-5476","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"article-number":"11795476261438872"}}