{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:55:40Z","timestamp":1777694140834,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Case Rep"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Post-streptococcal glomerulonephritis (PSGN) is a common cause of acute nephritic syndrome in children. Rarely, it may result in life-threatening complications, including acute pulmonary edema and critical hyperkalemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We report a 10-year-old Yemeni girl (25\u2009kg) presenting with severe respiratory distress, irritability, and generalized pitting edema. Laboratory tests confirmed PSGN with markedly reduced complement C3 (42.2\u2009mg\/dL) and nephritic urine sediment containing numerous red blood cells and casts. The patient developed critical hyperkalemia (7.0\u2009mmol\/L) and acute pulmonary edema, requiring urgent intubation and mechanical ventilation using pressure-controlled mandatory ventilation (P-CMV).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Management:<\/jats:title>\n                    <jats:p>Aggressive fluid mobilization and electrolyte stabilization were initiated. High-dose intravenous furosemide (4\u2009mg\/kg\/day) and low-dose dopamine (per local institutional protocols) were applied. Despite critical hyperkalemia, standard protocols (calcium, insulin-glucose) were unavailable; thus, potassium-lowering relied on continuous salbutamol and rapid diuresis. Appropriate adjunctive sedation was utilized briefly to facilitate mechanical ventilation. The patient produced 1700\u2009mL urine in 17\u2009hours, demonstrating a strong diuretic response. Continuous cardiac monitoring was maintained throughout the acute phase to mitigate arrhythmic complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Early recognition of severe extra-renal complications in PSGN is critical. Intensive supportive care\u2014including mechanical ventilation, meticulous fluid and electrolyte management, and appropriate sedation\u2014is essential for survival in cases of acute pulmonary edema and critical hyperkalemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795476261444444","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:49:20Z","timestamp":1776692960000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Post-streptococcal Glomerulonephritis Presenting With Acute Pulmonary Edema and Critical Hyperkalemia: A Rare Pediatric Case Report From Yemen"],"prefix":"10.1177","volume":"19","author":[{"given":"Ali Abdu Abdelbaky","family":"Mohamed","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Almansoor Polyclinic, Al-Hodaidah, Yemen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5155-963X","authenticated-orcid":false,"given":"Mansoor Khalid Mansoor","family":"Ayish","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Almansoor Polyclinic, Al-Hodaidah, Yemen"},{"name":"Department of Pediatrics, Emirates International University, Sana\u2019a, Yemen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5290-025X","authenticated-orcid":false,"given":"Hussein Mussa","family":"Muafa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Almansoor Polyclinic, Al-Hodaidah, Yemen"},{"name":"Department of Pediatrics, 21 September University for Medical and Applied Sciences, Sana\u2019a, Yemen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Hassanein M Gudsoorkar P Padala SA et al. Infection-Related Glomerulonephritis. StatPearls Publishing; January 2025. Updated December 13 2025. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538255\/"},{"key":"e_1_3_3_3_2","unstructured":"Ferretti JJ Stevens DL Fischetti VA eds. Streptococcus pyogenes: basic biology to clinical manifestations [Internet]. University of Oklahoma Health Sciences Center; 2016. Accessed April 13 2026. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK333424\/"},{"issue":"12","key":"e_1_3_3_4_2","article-title":"A comprehensive review study on glomerulonephritis associated with post-streptococcal infection","volume":"13","author":"Alhamoud MA","year":"2021","unstructured":"Alhamoud MA, Salloot IZ, Mohiuddin SS, et al. A comprehensive review study on glomerulonephritis associated with post-streptococcal infection. Cureus. 2021;13(12):e20212.","journal-title":"Cureus"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftae024"},{"key":"e_1_3_3_6_2","unstructured":"Geetha D. Poststreptococcal Glomerulonephritis. Medscape. Updated September 25 2023. Accessed December 21 2025. https:\/\/emedicine.medscape.com\/article\/240337-overview"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-004-1589-7"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.20944\/preprints202512.2608.v1"}],"container-title":["Clinical Medicine Insights: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476261444444","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795476261444444","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795476261444444","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:14:32Z","timestamp":1777454072000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795476261444444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":7,"alternative-id":["10.1177\/11795476261444444"],"URL":"https:\/\/doi.org\/10.1177\/11795476261444444","relation":{},"ISSN":["1179-5476","1179-5476"],"issn-type":[{"value":"1179-5476","type":"print"},{"value":"1179-5476","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"article-number":"11795476261444444"}}