{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:28:08Z","timestamp":1784366888020,"version":"3.55.0"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Circ Respir Pulm Med"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Dyspnea is reported in a minority of patients affected by coronavirus disease 2019 (COVID-19). Even patients with pneumonia can present hypoxemia without any respiratory distress, a phenomenon known as \u201csilent\u201d or \u201chappy hypoxemia\u201d. During the current pandemic there were only a few studies conducted on this subject and these were quite heterogeneous. Therefore, the prevalence of \u201csilent hypoxemia\u201d varied substantially. While studies did not show a clear tendency of \u201csilent hypoxemia\u201d to poorer outcomes compared to hypoxemia presenting with dyspnea, several showed that patients with \u201csilent hypoxemia\u201d are not protected from poor outcomes either. There is a need for a uniform definition of \u201csilent hypoxemia\u201d, in order to better guide clinicians and investigators. More studies are needed to shed light on the mechanisms of \u201csilent hypoxemia\u201d, as well as its presentation and influence in the disease's progression and outcomes, so as to better assist physicians in the care of COVID-19 patients.<\/jats:p>","DOI":"10.1177\/11795484221082761","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T08:40:11Z","timestamp":1645605611000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence, Presentation and Outcomes of Silent Hypoxemia in COVID-19"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5150-8395","authenticated-orcid":false,"given":"Am\u00e9lia","family":"Ribeiro","sequence":"first","affiliation":[{"name":"Pulmonology Department, Hospital Centre of Barreiro-Montijo, Barreiro, Portugal"},{"name":"Allergy Centre, CUF Descobertas Hospital, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Mendon\u00e7a","sequence":"additional","affiliation":[{"name":"Anesthesiology Department, Central Hospital of Funchal, Funchal, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e1udia","family":"Sabina Sousa","sequence":"additional","affiliation":[{"name":"Allergy Centre, CUF Descobertas Hospital, Lisboa, Portugal"},{"name":"Pulmonology Department, Central Hospital of Funchal, Funchal, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Trigueiro Barbosa","sequence":"additional","affiliation":[{"name":"Pulmonology Department, Hospital Centre of Barreiro-Montijo, Barreiro, Portugal"},{"name":"Allergy Centre, CUF Descobertas Hospital, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio","family":"Morais-Almeida","sequence":"additional","affiliation":[{"name":"Allergy Centre, CUF Descobertas Hospital, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,2,23]]},"reference":[{"key":"bibr1-11795484221082761","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"bibr2-11795484221082761","unstructured":"World Health Organization, R&D Blueprint and COVID-19. Accessed December 10th 2021. https:\/\/covid19.who.int\/."},{"key":"bibr3-11795484221082761","unstructured":"Report of the WHO-China joint mission on coronavirus disease 2019 (COVID-19). Accessed August 27th 2021. https:\/\/www.who.int\/docs\/default-source\/coronaviruse\/who-china-joint-mission-on-covid-19-final-report.pdf."},{"key":"bibr4-11795484221082761","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"bibr5-11795484221082761","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06033-2"},{"key":"bibr6-11795484221082761","unstructured":"Levitant R. The Infection That\u2019s Silently Killing Coronavirus Patients; The New York Times Opinion (updated April 26, 2020). 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