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Primary hyperparathyroidism can lead to a myriad of symptoms which not only decreases the quality of life of patients but also increases the risk of cardiovascular disease, osteoporosis, and kidney stones. Parathyroidectomy is the only known cure for the disease. This review explores the definition of asymptomatic primary hyperparathyroidism, the burden of disease, and the overwhelming benefits of parathyroidectomy.<\/jats:p>","DOI":"10.1177\/1179551418785135","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T04:47:20Z","timestamp":1530074840000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Should Symptoms Be Considered an Indication for Parathyroidectomy in Primary Hyperparathyroidism?"],"prefix":"10.1177","volume":"11","author":[{"given":"Alexandria D","family":"McDow","sequence":"first","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca S","family":"Sippel","sequence":"additional","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,6,27]]},"reference":[{"key":"bibr1-1179551418785135","doi-asserted-by":"crossref","unstructured":"Callendar GG, Udelsman R. 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