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The suggested causes of liver dysfunction include direct hepatocyte injury, co-morbid heart failure, associated autoimmune conditions (especially in the setting of Graves\u2019 Disease), preexisting liver disease and drugs including antithyroid medications. Although, some patients may have a pattern of mild liver injury, about 1% to 2% can have fulminant hepatitis. Liver enzymes can return to normalcy in as many as 77% to 83% of patients once the initiations of thionamides are started in a timely fashion, which can help forestall complications and prevent or minimize multi-organ dysfunction. Clinicians should maintain a high index of suspicion for underlying hyperthyroidism in patients presenting with unexplained liver dysfunction or unexplained jaundice.<\/jats:p>","DOI":"10.1177\/11795514221074672","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T00:21:29Z","timestamp":1644279689000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":62,"title":["Hyperthyroidism and Liver Dysfunction: A Review of a Common Comorbidity"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4257-7492","authenticated-orcid":false,"given":"Ernest","family":"Yorke","sequence":"first","affiliation":[{"name":"Department of Medicine & Therapeutics, University of Ghana Medical School, Accra, 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