{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T14:35:31Z","timestamp":1782311731171,"version":"3.54.5"},"reference-count":44,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Endocrinol Diabetes"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Abdominal obesity (AO) is associated with hyperuricemia (HU) in people with type 2 diabetes (T2DM), but most evidence comes from Asian studies and Latin American data are scarce. This study addresses that gap in a Peruvian setting. We aimed to evaluate the association between AO and HU in adult Peruvians diagnosed with T2DM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We carried out a cross-sectional observational study in adults with T2DM in a private clinic in Lima \u2013 Peru. We defined HU as serum uric acid\u2009\u2a7e\u20096\u2009mg\/dL and defined AO as waist circumference\u2009\u2a7e\u200994\u2009cm in men and \u2a7e88\u2009cm in women. In addition, we estimated crude and adjusted prevalence ratios (PRs) with 95% CIs for the AO\u2013HU association, adjusting for sex, glycosylated hemoglobin, estimated glomerular filtration rate, and systolic\/diastolic blood pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We evaluated 815 adults with T2DM. 62.6% were male, and the average age was 57\u2009years. AO was present in 82.9% and HU in 22.7%. The prevalence of HU in adults with AO was 24.3%, while the prevalence was 15.1% in those not obese. AO was associated with HU in the crude analysis (cPR: 1.60 95% CI 1.05-2.43) and remained statistically significant after adjustment for sex, glycosylated hemoglobin, estimated glomerular filtration rate, and systolic\/diastolic blood pressure (aPR: 1.95 95% CI 1.31-2.90).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In Peruvian adults with T2DM, abdominal obesity was associated with nearly double the prevalence of hyperuricemia. Because waist circumference is simple and low-cost to measure, integrating it into routine diabetes visits, along with targeted uric acid screening and management, may enhance cardiometabolic risk stratification and guide timely interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795514251403098","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T05:09:58Z","timestamp":1765429798000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Abdominal Obesity and Hyperuricemia in Peruvian Adults with Type 2 Diabetes Mellitus"],"prefix":"10.1177","volume":"18","author":[{"given":"F. Guadalupe","family":"Peralta-Vera","sequence":"first","affiliation":[{"name":"Universidad Peruana de Ciencias Aplicadas, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enzo","family":"Castillo-C\u00e9spedes","sequence":"additional","affiliation":[{"name":"Universidad Peruana de Ciencias Aplicadas, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucero Del Carmen","family":"Collazos-Huam\u00e1n","sequence":"additional","affiliation":[{"name":"Universidad Peruana de Ciencias Aplicadas, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3170-2254","authenticated-orcid":false,"given":"Camila","family":"Guerreros-Espino","sequence":"additional","affiliation":[{"name":"Universidad Peruana de Ciencias Aplicadas, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0282-6634","authenticated-orcid":false,"given":"Percy","family":"Herrera-A\u00f1azco","sequence":"additional","affiliation":[{"name":"Universidad Cient\u00edfica del Sur, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9158-1108","authenticated-orcid":false,"given":"Vicente A.","family":"Benites-Zapata","sequence":"additional","affiliation":[{"name":"Universidad San Ignacio de Loyola, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.15381\/anales.v78i2.13213"},{"key":"e_1_3_2_3_2","unstructured":"Federaci\u00f3n Latinoamericana de Sociedades de Obesidad. 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