{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T21:44:43Z","timestamp":1777585483561,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Endocrinol Diabetes"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Dyslipidemia is a condition where lipid metabolism is altered, and its mechanism is closely related to non-alcoholic fatty liver disease. The alteration of lipid metabolism during non-alcoholic fatty liver disease results in disrupted uptake, oxidation, and export. Assessing dyslipidemia among non-alcoholic fatty liver disease using these lipid panel is affordable, widely available, and compatible with existing laboratory infrastructure which enables for identifying individuals at increased risk of its complications, guiding therapeutic interventions, and supporting metabolic risk management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The study aimed to assess Dyslipidemia and its associated factors among non-alcoholic fatty liver disease-diagnosed type 2 diabetes mellitus patients in Adama Hospital Medical College, 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      An institution-based cross-sectional study design was used, and the study units were selected using a systematic random sampling technique. Sociodemographic, Behavioral, and Clinical data were collected using a structured questionnaire. Anthropometric measurements were taken by experienced nurses. Fasting venous blood was collected to test the lipid profiles and fasting blood glucose of study participants using Siemens Healthineers dimension EXL 200 chemistry analyzer. Data were assessed using STATA version 17 for correlation analysis among lipid parameters and the predictors, and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05 was considered statistically significant. Binary logistic regression was performed to show the statistically significant association among dyslipidemia and associated factors, and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05 was also considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The overall proportion of dyslipidemia was found to be 199 (85.04%). High TG 128 (54.7%) and low HDL-C 121 (51.71%) accounts for the major abnormal lipid parameters. BMI, blood pressure, and non-alcoholic fatty liver disease showed a weak positive statistical correlation with increased LDL-C, TG, and TC and a weak negative statistical correlation with HDL-C. The odds of lack of regular exercise and non-alcoholic fatty liver disease were higher for developing dyslipidemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The overall prevalence of dyslipidemia was found to be high among non-alcoholic fatty liver disease-diagnosed type 2 diabetes mellitus patients. Hypertriglyceridemia was found to be highly prevalent, followed by low HDL-C, and high LDL-C.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795514261436946","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T12:09:01Z","timestamp":1775477341000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Dyslipidemia and its Associated Factors Among Non-Alcoholic Fatty Liver Disease Diagnosed Type 2 Diabetes Mellitus Patients in Adama Hospital Medical College: A Cross-Sectional Study"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8967-4762","authenticated-orcid":false,"given":"Mahider Shimelis","family":"Feyisa","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Debre Tabor University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruktawit","family":"Eshetu","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahel Birhanu","family":"Arage","sequence":"additional","affiliation":[{"name":"Department of Midwifery, College of Health Sciences, Debre Tabor University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Besfat Berihun","family":"Erega","sequence":"additional","affiliation":[{"name":"Department of Midwifery, College of Health Sciences, Debre Tabor University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayenew","family":"Berhan","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Debre Tabor University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teklehaimanot","family":"Kiros","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Debre Tabor University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Getaneh","family":"Mola","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine and Health Sciences, University of Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ermias Bekele","family":"Enyew","sequence":"additional","affiliation":[{"name":"Department of Health Informatics, College of Medicine and Health Sciences, Wollo University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.14744\/hf.2023.2023.0042"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2024.03.006"},{"key":"e_1_3_3_4_2","article-title":"Global, regional, and national burden of NAFLD in youths and young adults aged 15\u201339 years, 1990\u20132021, its attributable risk factors, and projections to 2035: a systematic analysis of the global burden of disease study 2021","volume":"12","author":"Wang J","year":"2025","unstructured":"Wang J, Du J, Wang M, Jin M, Tang Z, Mao Y. Global, regional, and national burden of NAFLD in youths and young adults aged 15\u201339 years, 1990\u20132021, its attributable risk factors, and projections to 2035: a systematic analysis of the global burden of disease study 2021. Front Nutr. 2025;12:1509232.","journal-title":"Front Nutr"},{"key":"e_1_3_3_5_2","volume-title":"IDF Diabetes Atlas 11th Edition 2025: Global Prevalence and Projections for 2050","author":"Duncan BB","year":"2025","unstructured":"Duncan BB, Magliano DJ, Boyko EJ. IDF Diabetes Atlas 11th Edition 2025: Global Prevalence and Projections for 2050. Oxford University Press; 2025:gfaf177."},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-021-00448-y"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/jdr\/5555842"},{"issue":"2","key":"e_1_3_3_8_2","article-title":"Nonalcoholic fatty liver disease status and its associated factors among patients with type 2 diabetes mellitus in Adama Hospital Medical College, South Eastern Ethiopia: a cross-sectional study","volume":"9","author":"Feyisa MS","year":"2026","unstructured":"Feyisa MS, Ambachew S, Mebratie AF, et al. Nonalcoholic fatty liver disease status and its associated factors among patients with type 2 diabetes mellitus in Adama Hospital Medical College, South Eastern Ethiopia: a cross-sectional study. Heal Sci Rep. 2026;9(2):e71773.","journal-title":"Heal Sci Rep"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i47.8263"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v28i1.4"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnab037"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-021-00541-4"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.5897\/JDE2015.0086"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21249646"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2020.101092"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s41043-025-01054-3"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2024.112530"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17866"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2017.04.004"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2023.01.003"},{"key":"e_1_3_3_21_2","article-title":"Advancements in the treatment of non-alcoholic fatty liver disease (NAFLD)","volume":"13","author":"Rong L","year":"2022","unstructured":"Rong L, Zou J, Ran W, et al. Advancements in the treatment of non-alcoholic fatty liver disease (NAFLD). Front Endocrinol. 2022;13:1087260.","journal-title":"Front Endocrinol"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1493447"},{"key":"e_1_3_3_23_2","volume-title":"Guideline for the Pharmacological Treatment of Hypertension in Adults","author":"World Health Organization","year":"2021","unstructured":"World Health Organization. Guideline for the Pharmacological Treatment of Hypertension in Adults. World Health Organization; 2021."},{"key":"e_1_3_3_24_2","volume-title":"WHO Acceleration Plan to Stop Obesity","author":"World Health Organization","year":"2023","unstructured":"World Health Organization. WHO Acceleration Plan to Stop Obesity. World Health Organization; 2023."},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.13258"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13612"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-09172-9"},{"key":"e_1_3_3_28_2","first-page":"154","article-title":"Patterns of dyslipidemia among patients with non-alcoholic fatty liver disease: dyslipidemia among patients with NAFLD","author":"Shaikh KU","year":"2025","unstructured":"Shaikh KU, Kareem S, Sarfaraz A, Anwar MW, Batool N, Bakar SA. Patterns of dyslipidemia among patients with non-alcoholic fatty liver disease: dyslipidemia among patients with NAFLD. Pak J Heal Sci. 2025;6:154-160.","journal-title":"Pak J Heal Sci"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S319161"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-017-0217-z"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000913"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41387-024-00294-2"}],"container-title":["Clinical Medicine Insights: Endocrinology and Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795514261436946","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795514261436946","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795514261436946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T20:00:27Z","timestamp":1777406427000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795514261436946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":31,"alternative-id":["10.1177\/11795514261436946"],"URL":"https:\/\/doi.org\/10.1177\/11795514261436946","relation":{},"ISSN":["1179-5514","1179-5514"],"issn-type":[{"value":"1179-5514","type":"print"},{"value":"1179-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"article-number":"11795514261436946"}}