{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:57:12Z","timestamp":1792821432963,"version":"4.5.0"},"reference-count":39,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Oncol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The burden of human immunodeficiency virus (HIV) in cervical cancer remains a major public health challenge in developing countries, like Togo. Precancerous lesions include all cellular abnormalities that have malignant potential that can develop into cancer. The objective of this study was to determine the prevalence and factors associated with precancerous cervical lesions in HIV-infected women in our context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional descriptive study was carried out from November 31, 2022, to January 31, 2023, in an HIV care center in Lom\u00e9 (Non-Governmental Organization Espoir Vie Togo [NGO EVT] Grand-Lom\u00e9-Togo).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 271 women were included with a mean age of 47.0\u2009years and a standard deviation of 10.0\u2009years, among whom 20.7% do not have any scholar education. Only 6.7% of them had previously performed cervical smear examinations. The prevalence of precancerous cervical lesions observed in people living with human immunodeficiency virus (PLHIV) was 11.4% with a 95% confidence interval (CI) of 5.0 to 15.4. Cytological abnormalities were marked by low-grade squamous intraepithelial lesion (LSIL) (5.1%), followed by the presence of atypical squamous cells of undetermined significance (ASCUS) (3.5%). A statistically significant association was found between parity and the presence of precancerous lesions ( P\u2009=\u2009.014).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In this study, more than 1 out of 10 women living with HIV had precancerous cervical lesions, and parity was the factor associated. The implementation of a systematic screening program for precancerous cervical lesions and human papillomavirus (HPV) infection integrated into HIV care is necessary for early treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795549241234620","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T01:54:02Z","timestamp":1710899642000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Factors Associated With Precancerous Cervical Lesions in Human Immunodeficiency Virus\u2013Infected Women: A Cross-Sectional Survey in Togo"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6932-3540","authenticated-orcid":false,"given":"Tchin","family":"Darr\u00e9","sequence":"first","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"},{"name":"Faculty of Health Sciences, University of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toukilnan","family":"Djiwa","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karell Josiane Ogniad\u00e9","family":"Ladekpo","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingo K","family":"M\u2019Bortche","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baguilane","family":"Douaguibe","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoul-Samadou","family":"Aboubakari","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier Koumavi","family":"Ekou\u00e9vi","sequence":"additional","affiliation":[{"name":"Department of Health and Epidemiology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayaki","family":"Saka","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"bibr1-11795549241234620","doi-asserted-by":"publisher","DOI":"10.1684\/bdc.2014.2034"},{"key":"bibr2-11795549241234620","first-page":"399","volume":"90","author":"Pautier P","year":"2003","journal-title":"Bull Cancer"},{"key":"bibr3-11795549241234620","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S295137"},{"key":"bibr4-11795549241234620","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"bibr5-11795549241234620","first-page":"3407","volume":"18","author":"Darre T","year":"2017","journal-title":"Asian Pac J Cancer 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