{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:17:04Z","timestamp":1790731024962,"version":"4.1.0"},"reference-count":30,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Pediatr"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Neonatal sepsis is a serious blood bacterial infection in neonates at the age of equal to or less than 28\u2009days of life, and it\u2019s still the major significant cause of death and long-term morbidity in developing countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aimed to assess the prevalence and related factors with neonatal sepsis among newborns admitted to the neonatal intensive care unit at Hiwot Fana Comprehensive Specialized University Hospital, Harar, Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>An institutional-based retrospective cross-sectional study design was conducted among 386 neonates admitted to Neonatal Intensive Care Unit from September 2017 to August 2019. A systematic random sampling method was used. Data were analyzed using SPSS V.26. Descriptive summary statistics were done. Bivariate regression and multivariate analysis were computed. Variables with P-value &lt;.05 were declared as having a statistically significant association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>The prevalence of neonatal sepsis was 53.1%. Among the total neonates who had sepsis, 67.8% had early neonatal sepsis. Among neonatal factors, preterm neonates (AOR: 8.1, 95%CI: 2.1, 31.2), birth asphyxia (AOR: 4.7, 95%CI: 1.6, 13.6); and among maternal factors, urban residence (AOR: 0.26, 95%CI: 0.1, 0.5), antenatal care attendance (AOR: 0.32, 95%CI: 0.2, 0.6), spontaneous vaginal delivery (AOR: 0.047, 95%CI: 0.01, 0.2), and maternal antibiotic use (AOR: 0.39; 95%CI: 0.2, 0.8) were found to have significant association with neonatal sepsis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Overall, the magnitude of neonatal sepsis was high. Provision of neonatal and obstetrics care as per standard during prenatal, intranatal, and postnatal periods is needed. Training of health professionals on infection prevention and safe delivery practice should be provided.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795565241242656","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T08:38:02Z","timestamp":1711615082000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Determinants and Magnitude of Neonatal Sepsis at Hiwot Fana Comprehensive Specialized University Hospital, in Eastern Ethiopia: A Cross-Sectional Study"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1384-7123","authenticated-orcid":false,"given":"Astawus","family":"Alemayehu","sequence":"first","affiliation":[{"name":"Department of Public Health, Harar Health Science College, Harar, Ethiopia"},{"name":"Department of Nursing, Rift Valley University, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1091-9235","authenticated-orcid":false,"given":"Mohammed","family":"Yusuf","sequence":"additional","affiliation":[{"name":"Department of Nursing, Waliif Health Science and Business College, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8322-2570","authenticated-orcid":false,"given":"Abebaw","family":"Demissie","sequence":"additional","affiliation":[{"name":"Department of Nursing, Waliif Health Science and Business College, Harar, Ethiopia"},{"name":"Department of Anesthesia, Harar Health Science College, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2113-7076","authenticated-orcid":false,"given":"Mekuria Edae","family":"Muleta","sequence":"additional","affiliation":[{"name":"Department of Nursing, Waliif Health Science and Business College, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,28]]},"reference":[{"key":"bibr1-11795565241242656","volume-title":"Nelson Textbook of Pediatrics, 2-Volume Set","author":"Geme RMKJS","year":"2019"},{"key":"bibr2-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0287"},{"key":"bibr3-11795565241242656","unstructured":"World Health Organization. Sepsis. 2020. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/sepsis"},{"key":"bibr4-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70804-7"},{"key":"bibr5-11795565241242656","unstructured":"World Health Organization. Global report on the epidemiology and burden of sepsis: Current evidence, identifying gaps and future directions. World Health Organization; 2020."},{"key":"bibr6-11795565241242656","volume":"2019","author":"IGME UNI-aGfCMEU","year":"2020","journal-title":"Levels and Trends in Child Mortality: Report"},{"key":"bibr7-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60496-7"},{"key":"bibr8-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32989-7"},{"key":"bibr9-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2017-000347"},{"key":"bibr10-11795565241242656","volume-title":"Ethiopia Mini Demographic and Health Survey 2019","author":"Ethiopian Public Health Institute E, Federal Ministry of Health F and Icf","year":"2021"},{"key":"bibr11-11795565241242656","volume-title":"Ethiopia Demographic and Health Survey 2016: Key Indicators Report","author":"Central Statistical Agency aI","year":"2016"},{"key":"bibr12-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0107184"},{"key":"bibr13-11795565241242656","first-page":"1","volume":"9","author":"Mersha A","year":"2019","journal-title":"Res Rep Neonatol"},{"key":"bibr14-11795565241242656","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S276678"},{"key":"bibr15-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0154798"},{"key":"bibr16-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7801272"},{"key":"bibr17-11795565241242656","doi-asserted-by":"publisher","DOI":"10.15406\/jpnc.2020.10.00404"},{"key":"bibr18-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1177\/20503121211027044"},{"key":"bibr19-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0234472"},{"key":"bibr20-11795565241242656","volume":"8","author":"Bulto GA","year":"2021","journal-title":"Glob Pediatr Health"},{"key":"bibr21-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-019-0739-2"},{"key":"bibr22-11795565241242656","unstructured":"Unicef. Antenatal care: Antenatal care is essential for protecting the health of women and their unborn children. 2022. Accessed April 18 2023. https:\/\/data.unicef.org\/topic\/maternal-health\/antenatal-care\/"},{"key":"bibr23-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-020-02876-1"},{"key":"bibr24-11795565241242656","doi-asserted-by":"publisher","DOI":"10.4236\/ojog.2020.1090114"},{"key":"bibr25-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1016\/j.afjem.2022.07.013"},{"key":"bibr26-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-017-2573-1"},{"key":"bibr27-11795565241242656","first-page":"1811","volume":"4","author":"Gebrehiwot A","year":"2012","journal-title":"Der Pharmacia Lettre"},{"key":"bibr28-11795565241242656","first-page":"333","volume":"29","author":"Sorsa A.","year":"2019","journal-title":"Ethiop J Health Sci"},{"key":"bibr29-11795565241242656","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12887-016-0759-7","volume":"17","author":"Moges F","year":"2017","journal-title":"BMC Pediatr"},{"key":"bibr30-11795565241242656","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-14-104"}],"container-title":["Clinical Medicine Insights: Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795565241242656","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795565241242656","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795565241242656","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:41:55Z","timestamp":1777693315000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795565241242656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":30,"alternative-id":["10.1177\/11795565241242656"],"URL":"https:\/\/doi.org\/10.1177\/11795565241242656","relation":{},"ISSN":["1179-5565","1179-5565"],"issn-type":[{"value":"1179-5565","type":"print"},{"value":"1179-5565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"11795565241242656"}}