{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:14:24Z","timestamp":1792660464992,"version":"4.5.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The typical presentation of infantile hemangioma is well known and is easily recognizable. However, it may have many atypical presentations, as reported in the literature. Most of the hemangiomas are not visible at birth and become apparent at about 3 to 4 weeks of age. There are very few case reports of hemangioma presenting as a pale patch in the dermatology literature, and none of them describe the etiopathogenesis of this presentation and its clinical implications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective and Conclusion:<\/jats:title>\n                    <jats:p>We report a case of an infantile hemangioma with a trichrome presentation: an erythematous oval patch with a dark red macule at the periphery enclosed by a hypopigmented halo. A brief description of the etiopathogenesis of the pallor sign is also given.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Renseignements de base:<\/jats:title>\n                    <jats:p>La pr\u00e9sentation typique d'un h\u00e9mangiome infantile est bien connue et facilement reconnaissable. Toutefois, comme l'indique la documentation, il peut avoir de nombreuses pr\u00e9sentations atypiques. La plupart des h\u00e9mangiomes ne sont pas visibles \u00e0 la naissance et deviennent apparents \u00e0 environ 3 \u00e0 4 semaines. La documentation dermatologique ne compte que tr\u00e8s peu d'observations d'h\u00e9mangiome se pr\u00e9sentant sous forme de plaque p\u00e2le, et aucune d'entre elles ne d\u00e9crit l'\u00e9tiopathog\u00e9nie de cette pr\u00e9sentation et ses cons\u00e9quences cliniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectif et conclusion:<\/jats:title>\n                    <jats:p>Nous signalons un cas d'h\u00e9mangiome infantile avec pr\u00e9sentation trichrome: plaque \u00e9ryth\u00e9mateuse ovale avec une macule rouge fonc\u00e9e en p\u00e9riph\u00e9rie, entour\u00e9e d'un halo hypopigment\u00e9. Une br\u00e8ve description de l'\u00e9tiopathog\u00e9nie de la p\u00e2leur est \u00e9galement donn\u00e9e.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/120347541201600619","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T08:24:48Z","timestamp":1484468688000},"page":"451-452","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Pallor Sign: An Indicator of Hemangioma in Evolution"],"prefix":"10.1177","volume":"16","author":[{"given":"Muzamil","family":"Chisti","sequence":"first","affiliation":[{"name":"Department of Dermatology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nusrat","family":"Banka","sequence":"additional","affiliation":[{"name":"Department of Dermatology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Alfadley","sequence":"additional","affiliation":[{"name":"Department of Dermatology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,11,1]]},"reference":[{"key":"bibr1-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1972.tb16188.x"},{"key":"bibr2-120347541201600619","doi-asserted-by":"crossref","unstructured":"JacobsAH, WaltonRG. The incidence of birthmarks in the neonate. Pediatrics 1976;58:218\u201322.","DOI":"10.1542\/peds.58.2.218"},{"key":"bibr3-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-196607000-00013"},{"key":"bibr4-120347541201600619","doi-asserted-by":"crossref","unstructured":"EsterlyNB. Cutaneous hemangiomas, vascular stains and malformations, and associated syndromes. Curr Probl Dermatol 1995;3:72\u20133.","DOI":"10.1016\/S1040-0486(09)80020-3"},{"key":"bibr5-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1159\/000069960"},{"key":"bibr6-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2004.12.026"},{"key":"bibr7-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2005.3.234"},{"key":"bibr8-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.107.150284"},{"key":"bibr9-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1038\/nm1075"},{"key":"bibr10-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(00)80192-6"},{"key":"bibr11-120347541201600619","doi-asserted-by":"publisher","DOI":"10.1089\/153968503322758094"},{"key":"bibr12-120347541201600619","doi-asserted-by":"crossref","unstructured":"HerbertA, NgH, JessupW. Hypoxia regulates the production and activity of glucose transporter-1 and indoleamine 2, 3-dioxygenase in monocyte-derived endothelial-like cells: possible relevance to infantile haemangioma pathogenesis. Br J Dermatol 2011;164:308\u201315, doi:10.1111\/j.1365-2133.2010.10086.x,","DOI":"10.1111\/j.1365-2133.2010.10086.x"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/120347541201600619","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/120347541201600619","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:49:32Z","timestamp":1777391372000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/120347541201600619"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1177\/120347541201600619"],"URL":"https:\/\/doi.org\/10.1177\/120347541201600619","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}