{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:06:18Z","timestamp":1777514778497,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T00:00:00Z","timestamp":1429056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2015,9]]},"abstract":"\n Background:<\/jats:title>\n Systemic contact dermatitis occurs when a patient sensitized to an allergen topically is systemically reexposed to the allergen and develops a cutaneous eruption.<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n To report the case of a 48-year-old male who developed explosive dermatitis following injection of a formaldehyde-containing influenza vaccine and was subsequently shown to be strongly positive to formaldehyde and formaldehyde-releasing allergens by patch testing, as well as to review the literature for similar cases.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A PubMed search was made using the following search terms: systemic contact dermatitis, formaldehyde, influenza, and vaccine.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n A review of the literature revealed 2 cases of systemic contact dermatitis from formaldehyde derived from aspartame and 1 case from a thimerosal-containing influenza vaccine. No cases caused by formaldehyde in influenza or other vaccines were found.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This case highlights the importance of considering systemic allergic contact dermatitis in any patient presenting with dermatitis following injection of a formaldehyde-containing vaccine.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1203475415582306","type":"journal-article","created":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T23:02:06Z","timestamp":1429138926000},"page":"504-506","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination"],"prefix":"10.1177","volume":"19","author":[{"given":"L. Alexandra","family":"Kuritzky","sequence":"first","affiliation":[{"name":"Division of Dermatology, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Pratt","sequence":"additional","affiliation":[{"name":"Division of Dermatology, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,4,15]]},"reference":[{"key":"bibr1-1203475415582306","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e3182819c51"},{"key":"bibr2-1203475415582306","unstructured":"Novartis Pharmaceuticals. Novartis Agriflu influenza vaccine product monograph. http:\/\/www.novartis.ca\/en\/products\/vaccines\/products\/index.shtml?letter=a. Accessed November 26, 2014."},{"key":"bibr3-1203475415582306","unstructured":"Canadian Wood Council. Plywood. http:\/\/cwc.ca\/wood-products\/panel-products\/plywood\/. Accessed February 24, 2015."},{"key":"bibr4-1203475415582306","unstructured":"National Cancer Institute at the National Institute of Health. Formaldehyde and cancer risk. http:\/\/www.cancer.gov\/cancertopics\/factsheet\/Risk\/formaldehyde. Accessed February 24, 2015."},{"key":"bibr5-1203475415582306","first-page":"110","volume-title":"Fisher\u2019s Contact Dermatitis","author":"Rietschel RL","year":"2008","edition":"6"},{"key":"bibr6-1203475415582306","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2003.0225a.x"},{"key":"bibr7-1203475415582306","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02147.x"},{"key":"bibr8-1203475415582306","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61292-6"},{"key":"bibr9-1203475415582306","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-001-0091-6"},{"key":"bibr10-1203475415582306","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200506020-00002"},{"key":"bibr11-1203475415582306","unstructured":"AstraZeneca. FluMist influenza vaccine product monograph. http:\/\/www.astrazeneca.ca\/cs\/BlobServer?blobcol=pdffile&blobheader=application%2Fpdf&blobheadername1=Content-Disposition&blobheadername2=MDT-Type&blobheadervalue1=inline%3B+filename%3DProduct-Monograph.pdf&blobheadervalue2=abinary%3B+charset%3DUTF-8&blobkey=id&blobnocache=true&blobtable=AZ_FixedURLPDF&blobwhere=1285585473119&ssbinary=true. Accessed November 26, 2014."}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475415582306","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1203475415582306","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475415582306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:53:14Z","timestamp":1777391594000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1203475415582306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,15]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1177\/1203475415582306"],"URL":"https:\/\/doi.org\/10.1177\/1203475415582306","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,15]]}}}