{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:06:25Z","timestamp":1777514785768,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T00:00:00Z","timestamp":1429142400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Skin changes often signal systemic disease. Hypertrichosis lanuginosa acquisita (HLA) is a well-recognized symptom of internal malignancy defined as the adult onset of colourless, fine, lanugo-type hairs. To our knowledge, only 5 cases of HLA associated with endometrial malignancy have been reported in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of this report is to describe the clinical presentation of a patient with HLA associated with endometrial adenocarcinoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We report a patient presenting with atypical lanugo and weight loss who was diagnosed with HLA associated with endometrial adenocarcinoma. We summarize and critically review the 5 other known cases of endometrial malignancy associated with HLA reported in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The ectopic adult development of lanugo hair led to the diagnosis of endometrial adenocarcinoma. The diagnosis was made following computed tomography imaging and was confirmed by biopsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Continued vigilance and reporting of HLA will increase identification and understanding of this rare paraneoplastic condition. Family physicians should be aware of HLA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1203475415582319","type":"journal-article","created":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T22:41:33Z","timestamp":1429224093000},"page":"507-510","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Malignant Down"],"prefix":"10.1177","volume":"19","author":[{"given":"Daniel","family":"Dalcin","sequence":"first","affiliation":[{"name":"Northern Ontario School of Medicine, Thunder Bay, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney","family":"Manser","sequence":"additional","affiliation":[{"name":"Port Colborne Hospital, Port Colborne, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Mahler","sequence":"additional","affiliation":[{"name":"Northern Ontario School of Medicine, Thunder Bay, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,4,16]]},"reference":[{"key":"bibr1-1203475415582319","first-page":"507","volume":"2","author":"Turner M","year":"1865","journal-title":"Med Time Gaz"},{"key":"bibr2-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1987.00370110141021"},{"key":"bibr3-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08253.x"},{"key":"bibr4-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1159\/000250928"},{"key":"bibr5-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1980.tb07267.x"},{"key":"bibr6-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)80198-5"},{"key":"bibr7-1203475415582319","first-page":"479","volume":"47","author":"Kaiser IH","year":"1976","journal-title":"Obstet Gynecol"},{"key":"bibr8-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962013000100001"},{"key":"bibr9-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2006.00124.x"},{"key":"bibr10-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197510)36:4<1519::AID-CNCR2820360446>3.0.CO;2-H"},{"key":"bibr11-1203475415582319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb00468.x"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475415582319","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1203475415582319","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475415582319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:53:15Z","timestamp":1777391595000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1203475415582319"}},"subtitle":["Hypertrichosis Lanuginosa Acquisita Associated With Endometrial Adenocarcinoma"],"short-title":[],"issued":{"date-parts":[[2015,4,16]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1177\/1203475415582319"],"URL":"https:\/\/doi.org\/10.1177\/1203475415582319","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,16]]}}}