{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:08:12Z","timestamp":1777514892117,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,7,7]],"date-time":"2016-07-07T00:00:00Z","timestamp":1467849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Acne affects a large proportion of the Canadian population and has psychosocial and financial consequences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>We provide cost information for treatments recommended by the Canadian acne guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Highest level recommendations were selected for 3-month usage cost.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Three-month estimated treatment costs were as follows: topical retinoids ($14.40-$73.80), benzoyl peroxide (BPO; $6.75), fixed-dose BPO-clindamycin ($40.95-$44.10) and BPO-adapalene ($73.80), oral antibiotics ($25.20 for tetracycline 250 mg qid; $52.20 and $52.74 for doxycycline 50 mg bid and 100 mg od, respectively), and hormonal therapy ($26.46-$37.80 for ethinyl estradiol [EE] 0.030 mg\/drospirenone 3mg and $75.60-108.99 for EE 0.035 mg\/cyproterone acetate 2 mg). Oral isotretinoin 3-month costs ranged from $393.96 to $478.80.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Awareness of costs of recommended treatments may facilitate improved outcomes by increasing procurement and adherence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1203475416653735","type":"journal-article","created":{"date-parts":[[2016,6,9]],"date-time":"2016-06-09T15:47:40Z","timestamp":1465487260000},"page":"542-545","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Cost of Medications Recommended by Canadian Acne Clinical Practice Guidelines"],"prefix":"10.1177","volume":"20","author":[{"given":"Tiffany","family":"Czilli","sequence":"first","affiliation":[{"name":"Private practice, Family Medicine, Windsor, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry","family":"Tan","sequence":"additional","affiliation":[{"name":"Schulich School of Medicine and Dentistry, Windsor Campus, University of Western Ontario, Windsor, ON, Canada"},{"name":"Windsor Clinical Research, Ontario, Windsor, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja","family":"Knezevic","sequence":"additional","affiliation":[{"name":"Schulich School of Medicine and Dentistry, Windsor Campus, University of Western Ontario, Windsor, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Peters","sequence":"additional","affiliation":[{"name":"Independent pharmacist, Wellington Apothecary, Windsor, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,7]]},"reference":[{"key":"bibr1-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70442-6"},{"issue":"7","key":"bibr2-1203475416653735","first-page":"766","volume":"10","author":"Patel P","year":"2011","journal-title":"J Drugs Dermatol"},{"key":"bibr3-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.264"},{"key":"bibr4-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c5812"},{"key":"bibr5-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1986.tb05757.x"},{"key":"bibr6-1203475416653735","volume-title":"The Global Burden of Disease: Generating Evidence, Guiding Policy","author":"Institute for Health Metrics and Evaluation","year":"2013"},{"key":"bibr7-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.110901"},{"key":"bibr8-1203475416653735","unstructured":"Canadian Dermatology Association. Psychological effects of acne. 2014. http:\/\/www.dermatology.ca\/skin-hair-nails\/skin\/acne\/psychological-effects-of-acne\/. Accessed December 3, 2015."},{"key":"bibr9-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.140665"},{"key":"bibr10-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17591-0"},{"key":"bibr11-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.1998.1998015329.x"},{"key":"bibr12-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1991.tb00675.x"},{"key":"bibr13-1203475416653735","doi-asserted-by":"publisher","DOI":"10.3109\/09546639309082163"},{"key":"bibr14-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1991.tb01232.x"},{"issue":"9","key":"bibr15-1203475416653735","first-page":"2123","volume":"69","author":"Feldman S","year":"2004","journal-title":"Am Fam Physician"},{"key":"bibr16-1203475416653735","volume-title":"Guidelines for the Economic Evaluation of Health Technologies: Canada","author":"Canadian Agency for Drugs and Technologies in Health","year":"2006","edition":"3"},{"key":"bibr17-1203475416653735","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04374.x"},{"key":"bibr18-1203475416653735","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200809050-00001"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475416653735","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1203475416653735","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475416653735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:53:31Z","timestamp":1777391611000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1203475416653735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,7]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1177\/1203475416653735"],"URL":"https:\/\/doi.org\/10.1177\/1203475416653735","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,7]]}}}