{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:08:16Z","timestamp":1777514896144,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,7,7]],"date-time":"2016-07-07T00:00:00Z","timestamp":1467849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p>Although familial aggregation of lymphoproliferative disorders has been described, heredity has not been implicated in the etiology of primary cutaneous B-cell lymphomas (PCBCL). We report herein the first case of 2 young monozygotic twins with PCBCL. The first twin was an 18-year-old woman when she presented with multiple skin nodules on the thorax and head. Histology showed an atypical small B-cell proliferation, consistent with primary cutaneous marginal zone lymphoma (PCMZL). Molecular genetics studies demonstrated B-cell clonality. Seven years later, the second twin developed her first lesion that was histologically similar to that of her twin. She subsequently developed other clinically similar lesions. Histology was consistent with PCMZL and showed B-cell clonality. Occurrence of PCBCL in these monozygotic twins raises the possibility of a genetic risk factor. Further study of such rare cases may offer valuable insights into the molecular basis of the etiology and pathogenesis of this unusual disorder.<\/jats:p>","DOI":"10.1177\/1203475416658000","type":"journal-article","created":{"date-parts":[[2016,6,30]],"date-time":"2016-06-30T00:03:07Z","timestamp":1467244987000},"page":"582-585","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Primary Cutaneous B-Cell Lymphoma in Young Monozygotic Twins"],"prefix":"10.1177","volume":"20","author":[{"given":"Houda","family":"Bahig","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al (CHUM), Montr\u00e9al, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Petrogiannis-Haliotis","sequence":"additional","affiliation":[{"name":"Jewish General Hospital, McGill University, Montr\u00e9al, QC, Canada"},{"name":"McGill Multidisciplinary Cutaneous Lymphoma Clinic, Montr\u00e9al, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin L.","family":"Pehr","sequence":"additional","affiliation":[{"name":"Jewish General Hospital, McGill University, Montr\u00e9al, QC, Canada"},{"name":"McGill Multidisciplinary Cutaneous Lymphoma Clinic, Montr\u00e9al, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Roberge","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al (CHUM), Montr\u00e9al, QC, Canada"},{"name":"McGill Multidisciplinary Cutaneous Lymphoma Clinic, Montr\u00e9al, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,7]]},"reference":[{"key":"bibr1-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"bibr2-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200009000-00012"},{"key":"bibr3-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199906000-00014"},{"key":"bibr4-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2010.12.012"},{"key":"bibr5-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08239.x"},{"key":"bibr6-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-01-0140"},{"key":"bibr7-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.272"},{"key":"bibr8-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01543.x"},{"key":"bibr9-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200604000-00015"},{"key":"bibr10-1203475416658000","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.20.3.647"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475416658000","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1203475416658000","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475416658000","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:53:32Z","timestamp":1777391612000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1203475416658000"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2016,7,7]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1177\/1203475416658000"],"URL":"https:\/\/doi.org\/10.1177\/1203475416658000","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,7]]}}}