{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:08:23Z","timestamp":1777514903994,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T00:00:00Z","timestamp":1468800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2016,11]]},"abstract":"\n Importance:<\/jats:title>\n Scurvy remains prevalent in certain populations, including addicts, people of low socioeconomic status, and the severely malnourished. It classically presents as follicular hyperkeratosis and perifollicular hemorrhage of the lower extremities, as well as bleeding in other areas such as the gingiva and joints. This case presentation and literature review highlights the common pathophysiological findings associated with scurvy and current methods of diagnosis and treatment.<\/jats:p>\n <\/jats:sec>\n \n Observation:<\/jats:title>\n The patient described in this case presented with sudden oligoarthritis and purpura of the lower extremities. Following progression of the patient\u2019s symptoms and a low vitamin C serum concentration, the patient was treated with vitamin C supplementation and dramatically improved. This was considered to be the result of an underlying vitamin C deficiency secondary to insufficient fruit and vegetable intake due to allergies.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance:<\/jats:title>\n This case highlights the importance of maintaining a high index of suspicion for scurvy in atypical presentations of purpura not better explained by another disease or in additional populations at high risk of vitamin C deficiency. Early diagnosis by either a primary care physician or dermatologist can expedite the treatment process and improve patient prognosis.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1203475416660311","type":"journal-article","created":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T23:24:13Z","timestamp":1468538653000},"page":"592-595","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["A Case of Scurvy\u2014Uncommon Disease\u2014Presenting as Panniculitis, Purpura, and Oligoarthritis"],"prefix":"10.1177","volume":"20","author":[{"given":"Danielle","family":"Mintsoulis","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nataliya","family":"Milman","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Fahim","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,18]]},"reference":[{"key":"bibr1-1203475416660311","unstructured":"Health Canada. Monograph: Vitamin C. Ottawa, Canada: Health Canada; 2007. http:\/\/webprod.hc-sc.gc.ca\/nhpid-bdipsn\/monoReq.do?id=182. Accessed January 4, 2015."},{"key":"bibr2-1203475416660311","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70244-6"},{"key":"bibr3-1203475416660311","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.02844.x"},{"key":"bibr4-1203475416660311","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.05.061"},{"key":"bibr5-1203475416660311","first-page":"337","volume":"56","author":"Ordoukhanian E","year":"1995","journal-title":"Cutis"},{"key":"bibr6-1203475416660311","first-page":"920","volume":"125","author":"Raynaud E","year":"1998","journal-title":"Ann Dermatol Venereol"},{"key":"bibr7-1203475416660311","unstructured":"British Medical Journal Best Practice [Internet]. Vitamin C deficiency. London: BMJ; 2015. http:\/\/bestpractice.bmj.com\/best-practice\/monograph\/632\/highlights\/summary.html. Accessed December 28, 2015."},{"key":"bibr8-1203475416660311","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60366-3"},{"key":"bibr9-1203475416660311","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2005.01901.x"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475416660311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1203475416660311","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1203475416660311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:53:33Z","timestamp":1777391613000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1203475416660311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,18]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1177\/1203475416660311"],"URL":"https:\/\/doi.org\/10.1177\/1203475416660311","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,18]]}}}