{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:12:32Z","timestamp":1777515152133,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"deutsche forschungsgemeinschaft","doi-asserted-by":"publisher","award":["FE 1282\/2-1, GRK2099\/RTG2099"],"award-info":[{"award-number":["FE 1282\/2-1, GRK2099\/RTG2099"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>It is uncertain whether dermal regeneration templates (DRTs) are helpful to reconstruct nasal defects. The aim of this study was to assess whether the aesthetic subunits determine the outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this unicentric, retrospective study, the surgical procedures and outcomes of patients who received DRTs to reconstruct nasal defects were assessed and compared with the involved aesthetic subunits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>DRTs were used for reconstruction of 36 nasal defects in 35 patients with involvement of 76 aesthetic subunits: nasal sidewall (n = 21), nasal ala (n = 13), nasal tip\/columella (n = 12, n = 1, respectively), nasal dorsum (n = 12), and extranasal aesthetic areas (n = 17). Fifty-eight nasal and 8 extranasal aesthetic subunits were reconstructed with DRTs, 10 subunits with a flap. Twenty-nine of 36 defects healed without any complications (80.5%). All reconstructed nasal tips\/columella and the nasal dorsa healed without any complications. Region-specific complications were retraction of the ala rim (4\/12; 33.3% of the patients with involvement of the nasal ala) and the formation of a fistula in the nasal sidewall (1\/21; 4.8%). Region-specific complications of extranasal subunits were the development of an ectropium (2\/3; 66.7% of the patients with involvement of the lower lid).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>DRTs can be helpful to reconstruct nasal defects. However, if the defect involves the aesthetic subunits nasal ala or the infraorbital region, different techniques should be preferred.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1203475419852060","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T06:15:16Z","timestamp":1560147316000},"page":"413-420","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Reconstruction of Nasal Defects With Dermal Skin Substitutes\u2014A Retrospective Study of 36 Defects"],"prefix":"10.1177","volume":"23","author":[{"given":"Katharina","family":"Moratin","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, 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Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany"},{"name":"Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany"},{"name":"Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Faulhaber","sequence":"additional","affiliation":[{"name":"Dermatologische Gemeinschaftspraxis: Dr. Weller, Prof. Dr. Faulhaber & Kollegen, Schw\u00e4bisch Gm\u00fcnd, 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