{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:31:07Z","timestamp":1790267467833,"version":"4.1.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>This article aims to describe the cutaneous manifestations observed in the Zika epidemic in Peru during 2016 and 2017, as well as discuss the potential differential diagnoses. During the outbreak, the main reason for seeking medical advice was the development of a pruriginous maculopapular rash with a marked papular component, which started on the chest and later generalized to the rest of the body. Similar manifestations were noted in adults, children, and pregnant women. Other manifestations such as conjunctivitis, edema, or petechiae on the palate were rare. We suggest that in areas that are endemic for arboviral infections, in the differential diagnosis of a rash one must consider infections such as dengue, Zika, or chikungunya viruses. In nonendemic areas, the diagnosis is more difficult, as the rash may result from other viral infections not transmitted by arthropods and\/or reactive or inflammatory diseases (urticaria, atopic dermatitis, systemic lupus erythematosus). We recommend that primary care health personnel are trained in the recognition of the mucocutaneous lesions caused by Zika virus infection, which could contribute to the identification of suspicious cases, particularly pregnant women.<\/jats:p>","DOI":"10.1177\/1203475419878160","type":"journal-article","created":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T20:35:10Z","timestamp":1569530110000},"page":"33-40","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Cutaneous Manifestations of Zika in Peru"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1599-7811","authenticated-orcid":false,"given":"Willy","family":"Ramos","sequence":"first","affiliation":[{"name":"National Center of Epidemiology, Control and Prevention of Diseases, Ministry of Health, Lima, Peru"},{"name":"Institute of Clinical Research, National University of San Marcos, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Luna","sequence":"additional","affiliation":[{"name":"Epidemiology Office, Regional Health Department of Ica, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Alarc\u00f3n","sequence":"additional","affiliation":[{"name":"Epidemiology Office, Regional Health Department of Ica, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Santo Toribio de Mogrovejo University, Chiclayo, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"Santo Toribio de Mogrovejo University, Chiclayo, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Calder\u00f3n","sequence":"additional","affiliation":[{"name":"HAMPI: Consultoria en Salud, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4725-6284","authenticated-orcid":false,"given":"Ericson L.","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Peruvian National Institute of Health, Lima, Peru"},{"name":"Faculty of Human Medicine, Universidad de San Martin de Porres, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"bibr1-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-016-0172-y"},{"key":"bibr2-1203475419878160","doi-asserted-by":"publisher","DOI":"10.3201\/eid2207.151990"},{"key":"bibr3-1203475419878160","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2016.303112"},{"key":"bibr4-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31450-2"},{"key":"bibr5-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00502-X"},{"key":"bibr6-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1602113"},{"key":"bibr7-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1016\/j.apjtb.2016.04.004"},{"key":"bibr8-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760150192"},{"key":"bibr9-1203475419878160","doi-asserted-by":"crossref","first-page":"473","DOI":"10.20506\/rst.34.2.2372","volume":"34","author":"Choumet V","year":"2015","journal-title":"Rev Sci Tech"},{"key":"bibr10-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15831"},{"key":"bibr11-1203475419878160","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14636"},{"key":"bibr12-1203475419878160","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2016.31.3.331"},{"key":"bibr13-1203475419878160","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.9.20720"},{"issue":"25","key":"bibr14-1203475419878160","first-page":"844","volume":"26","author":"Mateo S.","year":"2017","journal-title":"Bol Epidemiol (Lima)"},{"key":"bibr17-1203475419878160","doi-asserted-by":"publisher","DOI":"10.17843\/rpmesp.2016.331.1900"},{"key":"bibr20-1203475419878160","volume-title":"Alerta epidemiol\u00f3gica AE-DEBE N\u00b0 001-2016. 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