{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:26:12Z","timestamp":1787617572252,"version":"build-2736575974"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:00:00Z","timestamp":1638144000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Psoriasis is a chronic inflammatory disease affecting multiple organ systems and resulting in reduced quality of life for many patients. A screening tool would be useful, particularly in underserviced or research settings with limited access to dermatologists. The Toronto Psoriatic Arthritis Screen, version 2 (ToPAS 2) is a validated screening tool for psoriatic arthritis containing questions specific for psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the performance of skin-specific questions from ToPAS 2 for the diagnosis of psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants aged &gt;18 were recruited from Dermatology and Family Medicine clinics and completed the ToPAS 2 questionnaire prior to being examined by a dermatologist for psoriasis. Two scoring indexes were derived from the ToPAS 2 skin-related questions using backward selection regression models. Statistical analysis was performed using receiver operating characteristic (ROC) curves to measure their performances.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Two hundred and fifty eight participants were recruited. 32 (12%) were diagnosed with psoriasis by dermatologist assessment. Index 1 includes all 5 skin-related questions from ToPAS 2, while Index 2 includes three of the five questions. Both indexes demonstrate high specificity (82% to 92%), sensitivity (69% to 84%), and excellent negative predictive value (NPV) (&gt;95%) for a diagnosis of psoriasis. The overall discriminatory power of these models is 0.823 (Index 1) and 0.875 (Index 2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Skin-related questions from ToPAS 2 have discriminatory value in detecting psoriasis, specifically questions relating to a family history, a prior physician diagnosis of psoriasis or a rash consistent with images of plaque psoriasis. This study is a valuable step in developing a screening tool for psoriasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/12034754211061085","type":"journal-article","created":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T06:25:02Z","timestamp":1638167102000},"page":"237-242","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of the Toronto Psoriatic Arthritis Screen 2 as a Screening Tool for Psoriasis"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0095-750X","authenticated-orcid":false,"given":"Jennifer H.","family":"Taylor","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Toronto Western Hospital, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maneka","family":"Deo","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Toronto Western Hospital, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Sutton","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Toronto Western Hospital, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Chandran","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Toronto Western Hospital, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sutha","family":"Shanmugarajah","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Toronto Western Hospital, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Toronto Western Hospital, ON, 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