{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:58:55Z","timestamp":1777514335053,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Objectives:<\/jats:title>\n                    <jats:p>Tumour necrosis factor-\u03b1 (TNF-\u03b1) inhibitors such as adalimumab and infliximab are commonly used in moderate-to-severe hidradenitis suppurativa (HS). While the impact of TNF-\u03b1 inhibitors on outcomes after an active infection in patients with HS has been explored, their effect on the SARS-CoV-2 vaccine response remains unknown. We investigated the impact of TNF-\u03b1 inhibitor therapy on the immunogenic response to the SARS-CoV-2 vaccine in patients with HS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a single-centre retrospective chart review of 120 patients with recorded levels of anti-SARS-CoV-2 spike antibody. This cohort was characterized descriptively by demographics, antibody levels, vaccine brand, number of doses, and days elapsed from vaccination. These variables were then compared by usage of anti-TNF therapy. Secondary analyses included comparison by biologic type, time on biologic, and biologic dosage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We found no significant difference in seroconversion following SARS-CoV-2 vaccination while on anti-TNF therapy in HS patients; a finding that holds in comparisons between anti-TNF therapy type, time exposed to biologic, and anti-TNF dosage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with HS on anti-TNF therapy receiving the SARS-CoV-2 mRNA vaccine seroconvert similarly as those without anti-TNF therapy, indicating this population should receive the vaccine and expect a similar degree of protection against COVID-19 compared to HS patients who do not receive anti-TNF therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/12034754251338809","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:32:40Z","timestamp":1747269160000},"page":"491-496","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["SARS-CoV-2 Vaccine Seroconversion in Patients With Hidradenitis Suppurativa Receiving Anti-TNF Therapy"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0802-0279","authenticated-orcid":false,"given":"Peter Y.","family":"Ch\u2019en","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avigdor","family":"Nosrati","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Keck School of Medicine of USC, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"McCall E.","family":"Torpey","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Toker","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5522-9668","authenticated-orcid":false,"given":"Zahidul","family":"Islam","sequence":"additional","affiliation":[{"name":"New York Medical College, Valhalla, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina L.","family":"Campton","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7774-1825","authenticated-orcid":false,"given":"Steven R.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Weill Cornell Medical College, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12082755"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19016"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljad069"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljad345"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2023.104788"},{"key":"e_1_3_2_7_2","volume-title":"StatPearls","author":"Gerriets V","year":"2023","unstructured":"Gerriets V, Goyal A, Khaddour K. 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