{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T14:45:32Z","timestamp":1792334732470,"version":"4.4.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Background:<\/jats:title>\n                  <jats:p>Lentigo maligna (LM), traditionally observed in older adults, is increasingly reported among younger patients, in whom diagnostic suspicion is lower.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To characterize clinical, dermoscopic, and reflectance confocal microscopy (RCM) features of LM in patients under and over 50\u2009years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This retrospective, single-centre study analyzed 200 patients with 229 biopsy-confirmed LM lesions diagnosed between 2018 and 2023. Patients were stratified by age (&lt;50 vs \u226550\u2009years). Clinical presentation, dermoscopic features, and RCM findings were analyzed using chi-square, Mann-Whitney\n                      <jats:italic toggle=\"yes\">U<\/jats:italic>\n                      tests, and linear regression (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 229 lesions, 33 occurred in patients &lt;50\u2009years. Younger patients, predominantly female (57% vs 40%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.067), showed less chronic actinic damage (41% vs 83%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) and more frequent trunk (36%) or lower limb (31%) lesions compared to older patients (face\/neck 26.7%, trunk 40%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.004). Lesions in younger patients tended to be more clinically noticeable and solitary, but showed fewer dermoscopic features (mean 3.26 vs 6.92,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001). The 4 most common dermoscopic patterns\u2014central featureless areas, irregular pigmentation foci, asymmetrical follicular pigmentation, and angular lines\u2014though less frequent in younger patients, remain useful for early LM diagnosis. All lesions displayed at least 1 atypical colour, with dark brown being the most frequent (87%). RCM (23 younger, 145 older patients) revealed cytoarchitectural atypia. Invasion rates (21.2% vs 22.6%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.86) were similar.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>LM in younger patients presents as clinically prominent but dermoscopically subtle lesions, necessitating heightened suspicion. The use of RCM may be of value to ensure accurate diagnosis and avoid inappropriate treatments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/12034754261418220","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T04:48:52Z","timestamp":1774932532000},"page":"518-523","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Lentigo Maligna and Lentigo Maligna Melanoma in Young Patients: What to Expect From the Unexpected?"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3019-3320","authenticated-orcid":false,"given":"Marta","family":"Menendez-Sanchez","sequence":"first","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyes","family":"Gamo-Villegas","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Uxua","family":"Florist\u00e1n-Muruzabal","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Alonso-Ca\u00f1as","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Pamp\u00edn-Franco","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Sarr\u00f3-Fuente","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Pinedo-Moraleda","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elia","family":"P\u00e9rez-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Departments of Research, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"L\u00f3pez-Estebaranz","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17951-3"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23852.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2012.05.006"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rce.2012.06.006"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2023.02.019"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0000000000000619"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1987.tb05843.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ced\/llad325"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ced\/llad089"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.038"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(00)90005-7"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2022.4302"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.84"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000489397"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.030"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15348"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1201a35"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14665"}],"container-title":["Journal 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