{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:41:23Z","timestamp":1792302083198,"version":"4.4.0"},"reference-count":42,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Nail conditions account for ~10% of dermatological conditions and can significantly impact quality of life. The NAIL-Q is a patient-reported outcome measure that was developed to measure outcomes that matter to patients treated for any type of fingernail or toenail condition. The ability of the NAIL-Q to detect change (ie, responsiveness) has not yet been established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the responsiveness of the NAIL-Q in patients undergoing treatment for nail psoriasis, onychomycosis, brittle nails, and retronychia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective validation study included patients newly diagnosed at an urban dermatology clinic in the United States. Participants completed the NAIL-Q at baseline, 3, and 6\u2009months. Responsiveness was evaluated by testing predefined hypotheses of the change score. Minimally important differences (MIDs) were calculated using anchor and distribution-based methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 166 eligible participants, 142 completed a baseline assessment and 79 (56%) and 55 (39%) completed the 3 and 6\u2009month follow-ups, respectively. Mean age of study participants was 56\u2009years (standard deviation\u2009=\u200919). Toenail conditions predominated (54%), with onychomycosis being the most common condition (54%). Hypothesis acceptance rates demonstrated validity of the change score for the Appearance 88% (15\/17), Nail Symptoms 80% (16\/20), and Outcome (treatment-related) 91% (10\/11) scales. Effect sizes were moderate for Appearance, Nail Distress, and Outcome scales (0.6-0.7). MID values for the 3 scales ranged from 9 to 14.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The NAIL-Q demonstrated sufficient evidence of responsiveness in patients undergoing treatment for nail psoriasis, onychomycosis, brittle nails, or retronychia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/12034754261427485","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:48:22Z","timestamp":1773830902000},"page":"498-503","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Responsiveness of the NAIL-Q Patient-Reported Outcome Measure"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2256-1984","authenticated-orcid":false,"given":"Carrie A.","family":"Forman","sequence":"first","affiliation":[{"name":"Department of Dermatology, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4309-4636","authenticated-orcid":false,"given":"Charlene","family":"Rae","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaya L.","family":"Curtis","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5152-9471","authenticated-orcid":false,"given":"Lucas","family":"Gallo","sequence":"additional","affiliation":[{"name":"Department of Surgery, McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"O\u2019Malley","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3193-5197","authenticated-orcid":false,"given":"Jade","family":"Conway","sequence":"additional","affiliation":[{"name":"Reveal Research Institute, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5913-9304","authenticated-orcid":false,"given":"Shari R.","family":"Lipner","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne F.","family":"Klassen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.03.062"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2021.05.009"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417716362"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.07.073"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2019.31.2.121"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000512688"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.05.143"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2165\/11592120-000000000-00000"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(98)70199-9"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03426.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.4137\/HSI.S11093"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-0054-x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03344.x"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1023\/a:1008986826756"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-4-50"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03362.x"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12664"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(99)70047-2"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00449429"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-018-1798-3"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-021-02222-1"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2021.4539"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2016.0509"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S429120"},{"key":"e_1_3_3_26_2","unstructured":"Mokkink LB Prinsen CA Patrick DL et al. COSMIN Study Design checklist for patient-reported outcome measurement instruments; 2019:1-32. https:\/\/www.cosmin.nl\/wp-content\/uploads\/COSMIN-study-designing-checklist_final.pdf"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-23-00040"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005029"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijosm.2018.03.003"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-020-00611-5"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9903-x"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002087"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-198903001-00015"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199007000-00008"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.201392"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1714"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1177\/03635465231152484"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-152"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.129968"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.2174\/1872213X13666191026090713"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2022.2044511"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/12034754261427485","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/12034754261427485","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/12034754261427485","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:17:11Z","timestamp":1792300631000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/12034754261427485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,18]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/12034754261427485"],"URL":"https:\/\/doi.org\/10.1177\/12034754261427485","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,18]]}}}