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The frequency of clinical manifestations in 65 patients with definite MS from Antioquia was compared with those reported from temperate regions. The most common manifestations were optic neuritis and motor symptoms with absence of cerebellar symptoms. This presentation is significantly different from the frequency distribution at onset in series from temperate regions. These differences suggest that environmental factors could modify the clinical expression of MS in this population.<\/jats:p>","DOI":"10.1177\/135245850100700403","type":"journal-article","created":{"date-parts":[[2007,1,18]],"date-time":"2007-01-18T20:03:56Z","timestamp":1169150636000},"page":"227-229","source":"Crossref","is-referenced-by-count":23,"title":["Clinical features of multiple sclerosis in a genetically homogeneous tropical population"],"prefix":"10.1177","volume":"7","author":[{"given":"J L","family":"S\u00e1nchez","sequence":"first","affiliation":[{"name":"Neurological Institute of Antioquia (NIA), University of Antioquia, Medellin, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L G","family":"Palacio","sequence":"additional","affiliation":[{"name":"Neurological Institute of Antioquia (NIA), University of Antioquia, Medellin, Colombia, Department of Biology, University of Antioquia, School of Medicine, Medellin, 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