{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T15:58:29Z","timestamp":1789919909184,"version":"4.0.1"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T00:00:00Z","timestamp":1200873600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:p>The presence of Chlamydia-like organism DNA was investigated by polymerase chain reaction (PCR) in cerebrospinal fluid (CSF) samples from 27 patients previously found positive for Chlamydia pneumoniae DNA: 12 with multiple sclerosis (MS), grouped according to clinical and magnetic resonance imaging (MRI) evidence of disease activity, 8 with other inflammatory neurological disorders and 7 with non-inflammatory neurological disorders. PCR evidence of Chlamydia-like organisms in CSF was observed only in two relapsing\u2013remitting MS patients with clinical and MRI disease activity. These findings suggest a possible association between C. pneumoniae and Chlamydia-like organism brain infections as a cofactor in MS development.<\/jats:p>","DOI":"10.1177\/1352458507085796","type":"journal-article","created":{"date-parts":[[2008,6,18]],"date-time":"2008-06-18T11:40:49Z","timestamp":1213789249000},"page":"564-566","source":"Crossref","is-referenced-by-count":11,"title":["Molecular detection of\n                    <i>Parachlamydia<\/i>\n                    -like organisms in cerebrospinal fluid of                 patients with multiple sclerosis"],"prefix":"10.1177","volume":"14","author":[{"given":"C","family":"Contini","sequence":"first","affiliation":[{"name":"Section of Infectious Diseases, Department of Clinical and Experimental                         Medicine, University of Ferrara, Ferrara, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Seraceni","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Clinical and Experimental                         Medicine, University of Ferrara, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Cultrera","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Clinical and Experimental                         Medicine, University of Ferrara, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Castellazzi","sequence":"additional","affiliation":[{"name":"Section of Neurology, University of Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Granieri","sequence":"additional","affiliation":[{"name":"Section of Neurology, University of Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Fainardi","sequence":"additional","affiliation":[{"name":"Section of Neurology, University of Ferrara, Italy; Neuroradiology Unit,                         Azienda Ospedaliera-Universitaria, Arcispedale S. Anna, Ferrara,                     Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,1,21]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-51-1-203"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.3109\/10408419409114556"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.10.5979-5985.2003"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.3201\/eid0906.020613"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.3201\/eid1204.050751"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1191\/1352458506ms1291oa"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1049oa"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1032"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1038\/339237a0"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1086\/431518"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2003.09.004"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458507085796","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458507085796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:23:25Z","timestamp":1777692205000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1352458507085796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,21]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1177\/1352458507085796"],"URL":"https:\/\/doi.org\/10.1177\/1352458507085796","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,21]]}}}