{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T15:34:14Z","timestamp":1791041654863,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,1,19]],"date-time":"2009-01-19T00:00:00Z","timestamp":1232323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:p>Background<\/jats:p>\n                  <jats:p>Bladder problems are very common in persons with multiple sclerosis (PwMS).<\/jats:p>\n                  <jats:p>Objective<\/jats:p>\n                  <jats:p>The aim of this study was to investigate the ability of PwMS to learn clean intermittent self-catheterization (CISC).<\/jats:p>\n                  <jats:p>Methods<\/jats:p>\n                  <jats:p>The physical disability of 23 PwMS was evaluated with the Expanded Disability Status Scale (EDSS), and cognitive status was evaluated with the Brief Repeatable Battery of Neuropsychological Tests (BRB-N). CISC was taught by the same continence advisor who was blinded to the cognitive test results. The ability to learn CISC was evaluated immediately after sessions and 3\u00a0months later. Twenty-three consecutive PwMS participated in the study.<\/jats:p>\n                  <jats:p>Results<\/jats:p>\n                  <jats:p>In all, 87% (20\/23) of the PwMS successfully finished CISC training. The number of lessons needed to acquire CISC skills differed significantly depending on the EDSS (Spearman r\u00a0=\u00a00.682, P\u00a0=\u00a00.0003), but the total cognitive decline subscore did not influence the ability to learn CISC. Only 13% (3\/23) of the PwMS failed to learn CISC. The ability to learn CISC depended on the number of lessons needed to acquire CISC ( r\u00a0=\u00a0\u22120.499, P\u00a0=\u00a00.0313) and the EDSS score ( r\u00a0=\u00a0\u22120.433, P\u00a0=\u00a00.0390) but not on the course of the disease ( r\u00a0=\u00a00.125, P\u00a0=\u00a00.5696) or on cognitive decline ( r\u00a0=\u00a0\u22120.311, P\u00a0=\u00a00.1480). After 3\u00a0months of follow-up, 30% (6\/20) of the PwMS had ceased performing CISC. A follow-up indicated no statistically significant correlations among any of the subscores of the cognitive test battery, the EDSS score, the course of the disease, and the time required to learn CISC and effective bladder management.<\/jats:p>\n                  <jats:p>Conclusions<\/jats:p>\n                  <jats:p>Our study thus confirmed that most (87%) PwMS were able to learn CISC in spite of cognitive dysfunction and therefore to improve their quality of life.<\/jats:p>","DOI":"10.1177\/1352458508098599","type":"journal-article","created":{"date-parts":[[2008,11,5]],"date-time":"2008-11-05T20:35:46Z","timestamp":1225917346000},"page":"379-384","source":"Crossref","is-referenced-by-count":52,"title":["Clean intermittent self-catheterization in persons with multiple sclerosis: the influence of cognitive dysfunction"],"prefix":"10.1177","volume":"15","author":[{"given":"L","family":"Vahter","sequence":"first","affiliation":[{"name":"Estonian MS Centre, West-Tallinn Central Hospital, Tallinn University, Tallinn, Estonia; Estonian MS Centre, West-Tallinn Central Hospital, Tallinn University, Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Zopp","sequence":"additional","affiliation":[{"name":"Institute of Psychology, Tallinn University, Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Kreegipuu","sequence":"additional","affiliation":[{"name":"Institute of Psychology, University of Tartu, Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Kool","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University of Tartu, Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Talvik","sequence":"additional","affiliation":[{"name":"Unit of Neurology, Tartu University Hospital Children\u2019s Clinic, Tartu, Estonia; Unit of Neurology, Tartu University Hospital Children\u2019s Clinic, Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Gross-Paju","sequence":"additional","affiliation":[{"name":"Institute of Psychology, Tallinn University, Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,1,19]]},"reference":[{"key":"atypb1","first-page":"239","volume-title":"A problem oriented approach in multiple sclerosis. Leuven: Uitgeverij Acco","author":"Petersen T","year":"1997"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200363020-00003"},{"key":"atypb3","first-page":"79","volume":"4","author":"Gross-Paju K","year":"2002","journal-title":"Int J MS Care"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.5.685"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200216070-00002"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1191\/1352458503ms893oa"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.5.692"},{"key":"atypb8","first-page":"50","volume":"6","author":"H\u00e4m\u00e4l\u00e4inen P","year":"1999","journal-title":"Int MS J"},{"key":"atypb9","first-page":"151","volume":"8","author":"Fischer JS","year":"1994","journal-title":"J Neurol Rehabil"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1080\/01688638908400907"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.5.1115"},{"key":"atypb12","unstructured":"12 Elpern SJ\u2004 Gunderson CH\u2004 Kattah J\u2004 Kirsch AD\u2004. Cognitive and memory functioning in recently diagnosed chronic multiple sclerosis. Paper presented at the meeting of the International Neuropsychological Society, Houston, USA; 1984."},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.53.1.103"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1080\/01688638608405173"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1080\/01688638908400926"},{"key":"atypb16","first-page":"865","volume":"6","author":"Heath A","year":"2000","journal-title":"J Clin Exp Neuropsychol"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.11.3.357"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1191\/0269215503cr586oa"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1191\/1352458505ms1110oa"},{"key":"atypb20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/ana.1032","volume":"50","author":"McDonald WI","year":"2001","journal-title":"Ann Neurol"},{"key":"atypb21","volume-title":"A manual for the brief repeatable battery of neuropsychological tests in multiple sclerosis.","author":"Rao SM","year":"1990"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458508098599","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458508098599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:25:06Z","timestamp":1777692306000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1352458508098599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,19]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["10.1177\/1352458508098599"],"URL":"https:\/\/doi.org\/10.1177\/1352458508098599","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,19]]}}}