{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:07:23Z","timestamp":1791331643510,"version":"4.3.1"},"reference-count":47,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2010,3,5]],"date-time":"2010-03-05T00:00:00Z","timestamp":1267747200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:p>\n                    The objective was to establish the extent to which physical functioning capacity and self-report measures are able to predict the habitual walking performance in ambulatory persons with multiple sclerosis. Fifty persons with multiple sclerosis (Expanded Disability Status Scale, EDSS, 1.5\u20146.5) were tested on leg muscle strength as well as walking and balance capacity, and completed self-report indices on perceived physical functioning. Habitual walking performance, that is, the real amount of steps that is performed in the customary living environment, was registered by means of an ambulant accelerometer-based monitor during seven consecutive days. Mild (EDSS 1.5\u20144.0,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 29) and moderate (EDSS 4.5\u20146.5,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 21) multiple sclerosis subgroups were additionally distinguished as predictor variables and values were hypothesized to differ depending on multiple sclerosis severity and concomitant ambulatory function. Multiple regression analyses yielded a single most significant predictor for each (sub)group with other variables making no independent contribution to the variation in habitual walking performance. For the total study sample, this was the 6-Minute Walking Test (\n                    <jats:italic toggle=\"yes\">\n                      R\n                      <jats:sup>2<\/jats:sup>\n                    <\/jats:italic>\n                    = 0.458,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.01). In the mild multiple sclerosis subgroup, the 6-Minute Walking Test was again most predictive, yet to a modest degree (\n                    <jats:italic toggle=\"yes\">\n                      R\n                      <jats:sup>2<\/jats:sup>\n                    <\/jats:italic>\n                    = 0. 187,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = 0.02). In the moderate multiple sclerosis subgroup, the 2-Minute Walking Test explained over half of the variance (\n                    <jats:italic toggle=\"yes\">\n                      R\n                      <jats:sup>2<\/jats:sup>\n                    <\/jats:italic>\n                    = 0.532,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.01). Habitual walking performance is best reflected by longer walking capacity tests. The extent to which it can be predicted based on clinical testing is larger in a multiple sclerosis patient sample with more severe walking disability. Ambulatory monitoring, however, includes aspects of community ambulation not captured in the clinic, and must be considered as an additional outcome for evaluating interventions in multiple sclerosis.\n                  <\/jats:p>","DOI":"10.1177\/1352458510361357","type":"journal-article","created":{"date-parts":[[2010,3,5]],"date-time":"2010-03-05T21:41:06Z","timestamp":1267825266000},"page":"618-626","source":"Crossref","is-referenced-by-count":136,"title":["Predicting habitual walking performance in multiple sclerosis: relevance of capacity and self-report measures"],"prefix":"10.1177","volume":"16","author":[{"given":"Domien","family":"Gijbels","sequence":"first","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium, , BIOMED Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert","family":"Alders","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Van Hoof","sequence":"additional","affiliation":[{"name":"SEIN Institute of Social and Psychological Sciences, Hasselt University, Diepenbeek, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Charlier","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Machteld","family":"Roelants","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Broekmans","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium, BIOMED Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bert","family":"Op 't Eijnde","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium, BIOMED Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Feys","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation and Health Care Research Centre, PHL University College, Hasselt, Belgium, BIOMED Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,3,5]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.5.962"},{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.60.1.31"},{"key":"e_1_2_1_3_1","article-title":"Patient perception of bodily functions in multiple sclerosis: gait and visual function are the most valuable","author":"Heesen C.","year":"2008","unstructured":"Heesen C., Bohm J., Reich C., Kasper J., Goebel M., Gold SM Patient perception of bodily functions in multiple sclerosis: gait and visual function are the most valuable. 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