{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:15:17Z","timestamp":1777936517650,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,7,10]],"date-time":"2012-07-10T00:00:00Z","timestamp":1341878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>Infectious mononucleosis (IM) is associated with the risk of developing multiple sclerosis (MS). Using databases of hospital admissions for England (1999\u20132005), we investigated the female-to-male ratios (FMRs) for admission to hospital for IM and MS stratified by age. Males were more frequently admitted for IM for all age groups apart from ages 10\u201314 (FMR 1.50; 95% confidence interval (CI) 1.36\u20131.64) and, borderline significantly, at ages 15\u201319 (FMR 1.03, 95% CI 0.99\u20131.08). This intriguing aspect of IM epidemiology in adolescence, the atypical female excess, may be linked to the sex ratio of MS, where females predominate from adolescence.<\/jats:p>","DOI":"10.1177\/1352458512450627","type":"journal-article","created":{"date-parts":[[2012,7,10]],"date-time":"2012-07-10T21:11:50Z","timestamp":1341954710000},"page":"359-361","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis"],"prefix":"10.1177","volume":"19","author":[{"given":"Sreeram V","family":"Ramagopalan","sequence":"first","affiliation":[{"name":"Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK"},{"name":"Department of Clinical Neurology, University of Oxford, Oxford, UK"},{"name":"Blizard Institute, Queen Mary University of London, Barts and the London School of Medicine and Dentistry, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"Giovannoni","sequence":"additional","affiliation":[{"name":"Blizard Institute, Queen Mary University of London, Barts and the London School of Medicine and Dentistry, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G","family":"Yeates","sequence":"additional","affiliation":[{"name":"Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Seagroatt","sequence":"additional","affiliation":[{"name":"Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J","family":"Goldacre","sequence":"additional","affiliation":[{"name":"Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,7,10]]},"reference":[{"key":"bibr1-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70094-6"},{"key":"bibr2-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70581-6"},{"key":"bibr3-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-200105000-00009"},{"key":"bibr4-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-009-9367-2"},{"key":"bibr5-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.1.72"},{"key":"bibr6-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70196-5"},{"key":"bibr7-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121369"},{"key":"bibr8-1352458512450627","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121577"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458512450627","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1352458512450627","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458512450627","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:34:56Z","timestamp":1777692896000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1352458512450627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,10]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1177\/1352458512450627"],"URL":"https:\/\/doi.org\/10.1177\/1352458512450627","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,10]]}}}