{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:30:46Z","timestamp":1781652646604,"version":"3.54.5"},"reference-count":15,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Visual symptoms are common in multiple sclerosis (MS). Low-contrast visual acuity (LCVA) testing using Sloan charts has demonstrated increased sensitivity for visual deficits compared to high-contrast acuity testing. Computerized testing of visual acuity may facilitate use in the clinic setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To evaluate the agreement between an iPad-based and Sloan testing of LCVA in a cohort of MS patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 38 patients with relapsing-remitting MS were enrolled after providing informed written consent at Partners MS Center, Brigham and Women\u2019s hospital. Monocular LCVA was measured using retroilluminated Sloan chart and iPad-based LogMAR chart. Number of correct letters and agreement between two measurements were assessed for each eye using Bland\u2013Altman analysis and paired t-test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>For both eyes, there was no significant difference in number correct between the two measurements using a paired t-test, and there was high correlation between two measurements (oculus dextrus (OD) r\u2009=\u20090.89, p\u2009&lt;\u20090.001; oculus sinister (OS) r\u2009=\u20090.78, p\u2009&lt;\u20090.001). The limits of agreement were \u22127.9 to +8.5 letters for the right eye and \u221210.9 to +11.2 letters for the left eye.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>An iPad-based LCVA test shows good agreement with Sloan testing in MS patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1352458517713667","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T11:13:48Z","timestamp":1496747628000},"page":"1126-1130","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Agreement analysis comparing iPad LCVA and Sloan testing in multiple sclerosis patients"],"prefix":"10.1177","volume":"24","author":[{"given":"Neda","family":"Sattarnezhad","sequence":"first","affiliation":[{"name":"Partners Multiple Sclerosis Center, Brigham and Women\u2019s Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Farrow","sequence":"additional","affiliation":[{"name":"Partners Multiple Sclerosis Center, Brigham and Women\u2019s Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorlan","family":"Kimbrough","sequence":"additional","affiliation":[{"name":"Partners Multiple Sclerosis Center, Brigham and Women\u2019s Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie","family":"Glanz","sequence":"additional","affiliation":[{"name":"Partners Multiple Sclerosis Center, Brigham and Women\u2019s Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Healy","sequence":"additional","affiliation":[{"name":"Partners Multiple Sclerosis Center, Brigham and Women\u2019s Hospital, Boston, MA, USA\/Biostatistics Center, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanuja","family":"Chitnis","sequence":"additional","affiliation":[{"name":"Partners Multiple Sclerosis Center, Brigham and Women\u2019s Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"bibr1-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu335"},{"key":"bibr2-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2013.10.008"},{"key":"bibr3-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000154521.40686.63"},{"key":"bibr4-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1177\/135245850000600305"},{"key":"bibr5-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.165449"},{"key":"bibr6-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1177\/135245859900500409"},{"key":"bibr7-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2012.03.009"},{"key":"bibr8-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181dbb664"},{"key":"bibr9-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000000173"},{"key":"bibr10-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517690822"},{"key":"bibr11-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1080\/10543400701329422"},{"key":"bibr12-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1177\/096228029900800204"},{"key":"bibr13-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1097\/01.opx.0000187863.12609.7b"},{"key":"bibr14-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-1935"},{"key":"bibr15-1352458517713667","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-1199"}],"container-title":["Multiple 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