{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:24:53Z","timestamp":1777937093479,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2018,4,20]],"date-time":"2018-04-20T00:00:00Z","timestamp":1524182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p>The present report discusses the case of a woman with neuromyelitis optica (NMO) who exhibited bilateral optic neuritis, longitudinally extensive myelitis, serum anti-aquaporin-4 antibodies, and a unique pattern of white matter involvement. The disease duration was 26\u2009years, and the patient died at the age of 65\u2009years. Sequential magnetic resonance images obtained during the last 6\u2009years of life revealed leukoencephalopathy-like lesions extending symmetrically and contiguously from the periventricular regions, which had begun to transform into multiple cavities with semi-annular partitions. This unique pattern of white matter abnormalities should thus be considered among those associated with NMO.<\/jats:p>","DOI":"10.1177\/1352458518763086","type":"journal-article","created":{"date-parts":[[2018,4,20]],"date-time":"2018-04-20T05:39:24Z","timestamp":1524202764000},"page":"1258-1261","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Contiguous and symmetrical disease expansion and massive necrosis of the cerebral white matter in a patient with neuromyelitis optica"],"prefix":"10.1177","volume":"24","author":[{"given":"Chiho","family":"Ishida","sequence":"first","affiliation":[{"name":"Department of Neurology, National Hospital Organization Iou Hospital, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokuhei","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Hospital Organization Iou Hospital, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyonobu","family":"Komai","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Hospital Organization Iou Hospital, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuya","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Hospital Organization Iou Hospital, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moeko","family":"Noguchi-Shinohara","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahito","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,4,20]]},"reference":[{"key":"bibr1-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001729"},{"key":"bibr2-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001367"},{"key":"bibr3-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12087"},{"key":"bibr4-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.3.390"},{"key":"bibr5-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1116-7"},{"key":"bibr6-1352458518763086","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1750-3639.2011.00475.x","volume":"21","author":"Matsuoka T","year":"2011","journal-title":"Brain Pathol"},{"key":"bibr7-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.20.11981"},{"key":"bibr8-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1177\/1352458514536253"},{"key":"bibr9-1352458518763086","doi-asserted-by":"publisher","DOI":"10.1191\/1352458505ms1236cr"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458518763086","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1352458518763086","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458518763086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:54:07Z","timestamp":1777694047000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1352458518763086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,20]]},"references-count":9,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1177\/1352458518763086"],"URL":"https:\/\/doi.org\/10.1177\/1352458518763086","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,20]]}}}