{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:55:18Z","timestamp":1780606518502,"version":"3.54.1"},"reference-count":11,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T00:00:00Z","timestamp":1540944000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Myelin oligodendrocyte glycoprotein antibodies (MOG-Abs) are a well-recognized cause of acquired demyelinating syndromes in both adult and children. Despite basal ganglia involvement on imaging, movement disorder is not a cardinal feature. We describe a 2-year-9-month-old girl who presented with severe encephalopathy with aphasia, seizures and a complex movement disorder with dystonic posturing and tonic eye deviation. Neuroimaging revealed subtle asymmetrical predominantly white matter signal changes. MOG-Abs were positive in the serum. Other known pathogenic autoantibodies including N-methyl-D-aspartate receptor antibodies (NMDAR-Abs) were negative. The patient made a complete recovery following 2-week corticosteroid treatment. This case highlights the need for MOG-Ab testing in children with suspected autoimmune encephalopathies.<\/jats:p>","DOI":"10.1177\/1352458518786074","type":"journal-article","created":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T12:00:28Z","timestamp":1540987228000},"page":"125-128","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Paediatric MOG antibody\u2013associated ADEM with complex movement disorder: A case report"],"prefix":"10.1177","volume":"25","author":[{"given":"Mario","family":"Sa","sequence":"first","affiliation":[{"name":"Department of Paediatric Neurology, Great Ormond Street Hospital for Children, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Thornton","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurophysiology, Great Ormond Street Hospital for Children, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WK Kling","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neuroradiology, Great Ormond Street Hospital for Children, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Kaliakatsos","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology, Great Ormond Street Hospital for Children, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Hacohen","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology, Great Ormond Street Hospital for Children, London, UK\/Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,10,31]]},"reference":[{"key":"bibr1-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000446"},{"key":"bibr2-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-316880"},{"key":"bibr3-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.4601"},{"key":"bibr4-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-018-8781-3"},{"key":"bibr5-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1604404"},{"key":"bibr6-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.3196"},{"key":"bibr7-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000322"},{"key":"bibr8-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328347b307"},{"key":"bibr9-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2012-303807"},{"key":"bibr10-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000443"},{"key":"bibr11-1352458518786074","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70310-1"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458518786074","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1352458518786074","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458518786074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:55:15Z","timestamp":1777694115000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1352458518786074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,31]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1177\/1352458518786074"],"URL":"https:\/\/doi.org\/10.1177\/1352458518786074","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,31]]}}}