{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:34Z","timestamp":1792787734396,"version":"4.5.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T00:00:00Z","timestamp":1591660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Turkish Association of Neurology","award":["2017"],"award-info":[{"award-number":["2017"]}]},{"DOI":"10.13039\/501100002657","name":"istanbul \u00fcniversitesi","doi-asserted-by":"publisher","award":["TDK-2017-23893"],"award-info":[{"award-number":["TDK-2017-23893"]}],"id":[{"id":"10.13039\/501100002657","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012317","name":"uclh biomedical research centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012317","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Overactive bladder (OAB) is common in patients with multiple sclerosis (MS) with a limited number of treatment options.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate the effect of transcutaneous tibial nerve stimulation (TTNS) and pelvic floor muscle training (PFMT) with biofeedback on OAB symptoms in female MS patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This study was conducted at the outpatient MS clinic in Istanbul. At baseline bladder diary, post-voiding residue (PVR), OAB, and Qualiveen Scales (QoL: Quality of Life; Siup: Specific Impact of Urinary Problems on QoL) were assessed. Patients were allocated to receive TTNS or PFMT daily for 6 weeks and reevaluated using the same tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifty-five patients (TTNS\u2009=\u200928, PFMT\u2009=\u200927) were included. Compared with baseline, both TTNS and PFMT groups improved in terms of OAB ( p\u2009=\u20090.0001, p\u2009=\u20090.0001), Qualiveen-siup ( p\u2009=\u20090.0001, p\u2009=\u20090.0001), Qualiveen-QoL ( p\u2009=\u20090.002, p\u2009=\u20090.006), PVR ( p\u2009=\u20090.0001, p\u2009=\u20090.21), frequency ( p\u2009=\u20090.0001, p\u2009=\u20090.69), nocturia ( p\u2009=\u20090.0001, p\u2009=\u20090.19), urgency ( p\u2009=\u20090.0001, p\u2009=\u20090.0001), and urge incontinence ( p\u2009=\u20090.0001, p\u2009=\u20090.0001). Between-group comparisons showed significant differences in 24-hour frequency ( p\u2009=\u20090.002) in favor of TTNS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study demonstrates the efficacy of both TTNS and PFMT for managing OAB symptoms in MS, associated with a significant impact on QoL, but did not show superiority of the methods. Further studies are needed to explore differences between these two non-invasive treatments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1352458520926666","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T04:53:59Z","timestamp":1591678439000},"page":"621-629","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Effectiveness of the transcutaneous tibial nerve stimulation and pelvic floor muscle training with biofeedback in women with multiple sclerosis for the management of overactive bladder"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3029-0446","authenticated-orcid":false,"given":"Cansu","family":"Polat Dunya","sequence":"first","affiliation":[{"name":"Florence Nightingale Faculty of Nursing, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeliha","family":"Tulek","sequence":"additional","affiliation":[{"name":"Florence Nightingale Faculty of Nursing, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"K\u00fcrt\u00fcnc\u00fc","sequence":"additional","affiliation":[{"name":"Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalesh N","family":"Panicker","sequence":"additional","affiliation":[{"name":"Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery and UCL Queen Square Institute of Neurology, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mefkure","family":"Eraksoy","sequence":"additional","affiliation":[{"name":"Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,6,9]]},"reference":[{"key":"bibr1-1352458520926666","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22374"},{"key":"bibr2-1352458520926666","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13010"},{"key":"bibr3-1352458520926666","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322011000900010"},{"key":"bibr4-1352458520926666","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2016.53"},{"key":"bibr5-1352458520926666","unstructured":"Blok B, Pannek P, Castro-Diaz D, et al. 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