{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:29:39Z","timestamp":1777937379864,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T00:00:00Z","timestamp":1591574400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000269","name":"economic and social research council","doi-asserted-by":"publisher","award":["RES-596-28-0001"],"award-info":[{"award-number":["RES-596-28-0001"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023670","name":"Nyckelfonden","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100023670","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"vetenskapsr\u00e0det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"name":"International Centre for Life Course Studies","award":["ES\/JO19119\/1"],"award-info":[{"award-number":["ES\/JO19119\/1"]}]},{"DOI":"10.13039\/501100003792","name":"hj\u00e3rnfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003792","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Evidence for the association between body mass index (BMI) and multiple sclerosis (MS) among men remains mixed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective and methods:<\/jats:title>\n                    <jats:p>Swedish military conscription and other registers identified MS after age of 20\u2009years and BMI at ages 16\u201320\u2009years ( N\u2009=\u2009744,548).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Each unit (kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) BMI increase was associated with greater MS risk (hazard ratio and 95% confidence interval\u2009=\u20091.034, 1.016\u20131.053), independent of physical fitness (1.021, 1.001\u20131.042). Categorised, overweight and obesity were associated with statistically significant raised MS risk compared to normal weight, but not after adjustment for physical fitness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>MS risk rises with increasing BMI, across the entire BMI range.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1352458520928061","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T04:57:10Z","timestamp":1591592230000},"page":"147-150","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Higher body mass index at ages 16 to 20\u2009years is associated with increased risk of a multiple sclerosis diagnosis in subsequent adulthood among men"],"prefix":"10.1177","volume":"27","author":[{"given":"Yin","family":"Xu","sequence":"first","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences, \u00d6rebro University, \u00d6rebro, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Hiyoshi","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences, \u00d6rebro University, \u00d6rebro, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith S","family":"Brand","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences, \u00d6rebro University, \u00d6rebro, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9811-908X","authenticated-orcid":false,"given":"Kelsi A","family":"Smith","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden\/Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahram","family":"Bahmanyar","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden\/Centre for Pharmacoepidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Alfredsson","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden\/Centre for Occupational and Environmental Medicine, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Olsson","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics, School of Medical Sciences, \u00d6rebro University, \u00d6rebro, Sweden\/Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden\/Department of Epidemiology and Public Health, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"key":"bibr1-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.187"},{"key":"bibr2-1352458520928061","doi-asserted-by":"publisher","DOI":"10.29245\/2572.942X\/2016\/7.1064"},{"key":"bibr3-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1159\/000450854"},{"key":"bibr4-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12718"},{"key":"bibr5-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1111\/apa.14881"},{"key":"bibr6-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.07.001"},{"key":"bibr7-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0108022"},{"key":"bibr8-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/72.3.690"},{"key":"bibr9-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25036"},{"key":"bibr10-1352458520928061","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2016.02.010"}],"container-title":["Multiple 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Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458520928061","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1352458520928061","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1352458520928061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:03:33Z","timestamp":1777694613000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1352458520928061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,8]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1177\/1352458520928061"],"URL":"https:\/\/doi.org\/10.1177\/1352458520928061","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,8]]}}}