{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:29:33Z","timestamp":1777937373741,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T00:00:00Z","timestamp":1594857600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671283"],"award-info":[{"award-number":["81671283"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81701266"],"award-info":[{"award-number":["81701266"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To validate the recently proposed imaging criteria in distinguishing aquaporin-4 antibody (AQP4-ab)-seropositive neuromyelitis optica spectrum disorder (NMOSD) from multiple sclerosis (MS) and myelin oligodendrocyte glycoprotein antibody-associated disorder (MOG-AD) at disease onset in a Chinese population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We enrolled 241 patients in this retrospective study, including 143 AQP4-ab-seropositive NMOSD, 73 MS, and 25 MOG-AD. Cacciaguerra\u2019s criteria were described as fulfillment of at least 2\/5 conditions including the absence of the combined juxtacortical\/cortical lesions, the presence of longitudinal extensive transverse myelitis (LETM) lesions, the presence of periependymal-lateral ventricles lesions, the absence of Dawson\u2019s fingers lesions, and the absence of periventricular lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fulfillment of at least 3\/5 conditions was able to differentiate NMOSD from MS with a good diagnostic performance (accuracy\u2009=\u20090.92, sensitivity\u2009=\u20090.91, specificity\u2009=\u20090.93), yet failed to differentiate NMOSD from MOG-AD. LETM lesions showed the highest accuracy (0.78), sensitivity (0.70), and specificity (0.97) for NMSOD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our research suggested the utility of Cacciaguerra\u2019s criteria in a Chinese population at disease onset. A better diagnostic performance in NMOSD could be attained with at least 3\/5 conditions fulfilled. Yet their utility in distinguishing NMOSD from MOG-AD was limited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1352458520939008","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T06:17:05Z","timestamp":1594880225000},"page":"871-882","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Evaluation of brain and spinal cord lesion distribution criteria at disease onset in distinguishing NMOSD from MS and MOG antibody-associated disorder"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1835-5734","authenticated-orcid":false,"given":"Meng-Ting","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4462-171X","authenticated-orcid":false,"given":"Yin-Xi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3145-7778","authenticated-orcid":false,"given":"Mei-Ping","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 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