{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T11:23:44Z","timestamp":1784201024356,"version":"3.55.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Oral cladribine is an approved disease-modifying drug for the treatment of relapsing multiple sclerosis. In controlled clinical trials as well as in post marketing safety assessments, autoimmune conditions have not yet been reported as a specific side effect of cladribine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective and Results:<\/jats:title>\n                    <jats:p>Here, we report a case of anti-glomerular basement membrane antibody-mediated glomerulonephritis that occurred shortly after the fourth cladribine treatment cycle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Neurologists should be attentive to the development of secondary autoimmunity in cladribine-treated patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13524585211022719","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T11:45:54Z","timestamp":1624535154000},"page":"1960-1964","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Autoimmune glomerulonephritis in a multiple sclerosis patient after cladribine treatment"],"prefix":"10.1177","volume":"27","author":[{"given":"Kristina","family":"Sch\u00f6nfelder","sequence":"first","affiliation":[{"name":"Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene","family":"Schuh","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick","family":"Pfister","sequence":"additional","affiliation":[{"name":"Department of Nephropathology, University Medicine Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Kr\u00e4mer","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology, University Hospital M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"Eisenberger","sequence":"additional","affiliation":[{"name":"Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Skuljec","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Hackert","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Ruck","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology, University Hospital M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5171-4845","authenticated-orcid":false,"given":"Steffen","family":"Pfeuffer","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology, University Hospital M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Fleischer","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"G\u00e4ckler","sequence":"additional","affiliation":[{"name":"Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Hagenacker","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kribben","sequence":"additional","affiliation":[{"name":"Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven G","family":"Meuth","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology, University Hospital M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Kleinschnitz","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Refik","family":"Pul","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medicine Essen, Essen, Germany\/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,6,24]]},"reference":[{"key":"bibr1-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92826-2"},{"key":"bibr2-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2019.01.038"},{"key":"bibr3-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2019.02.018"},{"key":"bibr4-13524585211022719","volume-title":"Annual meeting of the European Committee on Treatment and Research in Multiple Sclerosis (ECTRIMS) Poster P977","author":"Giovannoni G"},{"key":"bibr5-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0902533"},{"key":"bibr6-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517727603"},{"key":"bibr7-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70005-5"},{"key":"bibr8-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1177\/1352458510391344"},{"key":"bibr9-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2018.11.021"},{"key":"bibr10-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfx057"},{"key":"bibr11-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2016.06.016"},{"key":"bibr12-13524585211022719","first-page":"1541","volume":"152","author":"Tipping PG","year":"1998","journal-title":"Am J Pathol"},{"key":"bibr13-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012070705"},{"key":"bibr14-13524585211022719","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2319"},{"key":"bibr15-13524585211022719","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.10583.1"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13524585211022719","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/13524585211022719","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13524585211022719","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:06:50Z","timestamp":1777694810000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/13524585211022719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,24]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1177\/13524585211022719"],"URL":"https:\/\/doi.org\/10.1177\/13524585211022719","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,24]]}}}