{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:32:02Z","timestamp":1790652722050,"version":"4.1.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:00:00Z","timestamp":1674518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS113828"],"award-info":[{"award-number":["R01NS113828"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Data on corpus callosum involvement in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of the study was to compare callosal lesions in MOGAD, multiple sclerosis (MS), and aquaporin-4-IgG positive neuromyelitis optica spectrum disorder (AQP4+NMOSD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Callosal lesion frequency was similar in MOGAD (38\/171 (22%)), MS (24\/72 (33%)), and AQP4+NMOSD (18\/63 (29%)). Clinical phenotypes included encephalopathy (47%) and focal supratentorial (21%) or infratentorial (45%) deficits. None had callosal-disconnection syndromes. Maximal callosal-T2-lesion diameter (median (range)) in millimeter was similar in MOGAD (21 (4\u201377)) and AQP4+NMOSD (22 (5\u201349); p\u2009=\u20090.93) but greater than in MS (10.5 (2\u201364)). Extracallosal extension (21\/38 (55%)) and T2-lesion resolution (19\/34 (56%)) favored MOGAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Despite similar frequency and imaging overlap, larger lesions, sagittal midline involvement, and lesion resolution favored MOGAD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13524585221150743","type":"journal-article","created":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T03:37:47Z","timestamp":1674531467000},"page":"748-752","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Corpus callosum involvement in MOG antibody-associated disease in comparison to AQP4-IgG-seropositive neuromyelitis optica spectrum disorder and multiple sclerosis"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7089-188X","authenticated-orcid":false,"given":"Nicholas H","family":"Chia","sequence":"first","affiliation":[{"name":"Department of Neurology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6400-7760","authenticated-orcid":false,"given":"Vyanka","family":"Redenbaugh","sequence":"additional","affiliation":[{"name":"Department of Neurology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J","family":"Chen","sequence":"additional","affiliation":[{"name":"Departments of Neurology and Ophthalmology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8387-6491","authenticated-orcid":false,"given":"Sean J","family":"Pittock","sequence":"additional","affiliation":[{"name":"Departments of Neurology and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6661-2910","authenticated-orcid":false,"given":"Eoin P","family":"Flanagan","sequence":"additional","affiliation":[{"name":"Departments of Neurology and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,24]]},"reference":[{"key":"bibr1-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00218-0"},{"key":"bibr2-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000012467"},{"key":"bibr3-13524585221150743","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.722404"},{"key":"bibr4-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aww350"},{"key":"bibr5-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2019.116430"},{"key":"bibr6-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1177\/1352458509103301"},{"key":"bibr7-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2019.04.019"},{"key":"bibr8-13524585221150743","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.600169"},{"issue":"12","key":"bibr9-13524585221150743","first-page":"1374","volume":"86","author":"Garg N","year":"2015","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"bibr10-13524585221150743","doi-asserted-by":"publisher","DOI":"10.1002\/ana.26549."}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13524585221150743","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/13524585221150743","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13524585221150743","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:11:22Z","timestamp":1777695082000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/13524585221150743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,24]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1177\/13524585221150743"],"URL":"https:\/\/doi.org\/10.1177\/13524585221150743","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,24]]}}}