{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T03:18:09Z","timestamp":1779333489605,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"11-12","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>The vaccination with live attenuated vaccines is generally not recommended during natalizumab (NTZ), as it is included among immunosuppressive\/immunomodulating therapies. Nevertheless, considering the lack of evidence of a non-Central Nervous System (CNS) immunosuppressive effect of NTZ, after a risk\/benefit evaluation, we decided to vaccinate four multiple sclerosis (MS) patients (three with an indication to switch to ocrelizumab for high-risk Progressive Multifocal Leukoencephalopathy (PML) and one for pregnancy planning). No vaccine-related adverse events of any type nor varicella zoster virus (VZV) infections were observed. To the best of our knowledge, these case series represent the first description of the good safety profile of anti-VZV vaccination in MS patients during NTZ treatment.<\/jats:p>","DOI":"10.1177\/13524585231204121","type":"journal-article","created":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T04:34:06Z","timestamp":1696307646000},"page":"1514-1517","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Safety of anti-varicella zoster virus vaccination in patients with multiple sclerosis treated with natalizumab: A case series"],"prefix":"10.1177","volume":"29","author":[{"given":"Caterina","family":"Lapucci","sequence":"first","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2507-4025","authenticated-orcid":false,"given":"Vincenzo Daniele","family":"Boccia","sequence":"additional","affiliation":[{"name":"Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Sirito","sequence":"additional","affiliation":[{"name":"Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Cellerino","sequence":"additional","affiliation":[{"name":"Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malgorzata","family":"Mikulska","sequence":"additional","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino, Genoa, Italy"},{"name":"Division of Infectious Diseases, Department of Health Sciences, University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Sticchi","sequence":"additional","affiliation":[{"name":"Hygiene Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy"},{"name":"Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matilde","family":"Inglese","sequence":"additional","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino, Genoa, Italy"},{"name":"Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,3]]},"reference":[{"key":"bibr1-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2018.4905"},{"key":"bibr2-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.21"},{"key":"bibr3-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008157"},{"key":"bibr4-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2021.103581"},{"key":"bibr5-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1177\/1352458520952310"},{"key":"bibr6-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2020.02.006"},{"key":"bibr7-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2019.3365"},{"key":"bibr8-13524585231204121","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2021.01.009"},{"key":"bibr9-13524585231204121","unstructured":"Centers for Disease Control and Prevention. 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