{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:51:38Z","timestamp":1792036298132,"version":"4.4.0"},"reference-count":207,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T00:00:00Z","timestamp":1707955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Epidemiological data reveal that 45% of persons with multiple sclerosis (PwMS) in France are more than 50\u2009years. This population more than 50 is more susceptible to cancer, and this risk may be increased by frequent use of immunosuppressive drugs. Consequently, concerns have arisen about the potential increased risk of cancer in PwMS and how patients should be screened and managed in terms of cancer risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To develop evidence-based recommendations to manage the coexistence of cancer and multiple sclerosis (MS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The French Group for Recommendations in MS collected articles from PubMed and university databases covering the period January 1975 through June 2022. The RAND\/UCLA method was employed to achieve formal consensus. MS experts comprehensively reviewed the full-text articles and developed the initial recommendations. A group of multidisciplinary health care specialists then validated the final proposal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Five key questions were addressed, encompassing various topics such as cancer screening before or after initiating a disease-modifying therapy (DMT), appropriate management of MS in the context of cancer, recommended follow-up for cancer in patients receiving a DMT, and the potential reintroduction of a DMT after initial cancer treatment. A strong consensus was reached for all 31 recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>These recommendations propose a strategic approach to managing cancer risk in PwMS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13524585231223880","type":"journal-article","created":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T08:07:50Z","timestamp":1707984470000},"page":"899-924","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Cancer and multiple sclerosis: 2023 recommendations from the French Multiple Sclerosis Society"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3683-5582","authenticated-orcid":false,"given":"Nicolas","family":"Collongues","sequence":"first","affiliation":[{"name":"Department of Neurology, University Hospital of Strasbourg, Strasbourg, France"},{"name":"Center for Clinical Investigation, INSERM U1434, Strasbourg, France"},{"name":"Biopathology of Myelin, Neuroprotection and Therapeutic Strategy, INSERM U1119, Strasbourg, France"},{"name":"Department of Pharmacology, Addictology, Toxicology, and Therapeutics, Strasbourg University, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Durand-Dubief","sequence":"additional","affiliation":[{"name":"Service de Scl\u00e9rose en Plaques, Pathologies de la My\u00e9line et Neuro-Inflammation, H\u00f4pital Neurologique Pierre Wertheimer, Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Lebrun-Frenay","sequence":"additional","affiliation":[{"name":"Department of Neurology, CHU Nice, Nice, France"},{"name":"Universit\u00e9 C\u00f4te d\u2019Azur, UMR2CA-URRIS, Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9860-7657","authenticated-orcid":false,"given":"Bertrand","family":"Audoin","sequence":"additional","affiliation":[{"name":"Department of Neurology, CRMBM, APHM, Aix-Marseille University, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3834-2981","authenticated-orcid":false,"given":"Xavier","family":"Ayrignac","sequence":"additional","affiliation":[{"name":"Department of Neurology, Montpellier University Hospital, Montpellier, France"},{"name":"University of Montpellier, Montpellier, France"},{"name":"INM, INSERM, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Bensa","sequence":"additional","affiliation":[{"name":"Department of Neurology, H\u00f4pital Fondation Adolphe de Rothschild, Paris, 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