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Children with multiple sclerosis ( n\u2009=\u2009346) aged 9\u201317 were analyzed with logistic and Poisson regression. Control groups included children with Crohn\u2019s disease, psoriasis, and no autoimmune diseases. The results indicated a negative association between vaccinations and pediatric multiple sclerosis, with no significant risk identified. This negative relationship was consistent in sensitivity and clinically isolated syndrome analyses. 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