{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:38:28Z","timestamp":1787236708306,"version":"build-2736575974"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T00:00:00Z","timestamp":1735257600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>\n                    Trigeminal neuralgia (TN) is commonly associated with multiple sclerosis (MS). Whether TN should be considered a clinical relapse or evidence of active disease lacks consensus. TN was diagnosed in 0.9%\u20131.9% (\n                    <jats:italic>n<\/jats:italic>\n                    = 171) of people with multiple sclerosis (pwMS) at three international sites. In 9.9%, TN was their first potential demyelinating symptom. In 86%, TN onset occurred a median of 13\u201316 years after MS diagnosis. A clinical relapse occurred within 6 months of TN onset in 20% of pwMS. These data suggest TN onset should be evaluated as active disease and incorporated in diagnostic and therapeutic decisions in MS.\n                  <\/jats:p>","DOI":"10.1177\/13524585241309257","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T07:53:31Z","timestamp":1735286011000},"page":"607-611","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Trigeminal neuralgia within the disease course of MS: Diagnostic and therapeutic implications from a multicenter cohort"],"prefix":"10.1177","volume":"31","author":[{"given":"Sini M","family":"Laakso","sequence":"first","affiliation":[{"name":"Department of Neurology, Brain Center, Helsinki University Hospital, Helsinki, Finland"},{"name":"Translational Immunology Research Program, University of Helsinki, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiwon","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Neurology, St. Michael\u2019s Hospital, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fasna","family":"Raufdeen","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Neurology, St. Michael\u2019s Hospital, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5636-0716","authenticated-orcid":false,"given":"Ashley","family":"Jones","sequence":"additional","affiliation":[{"name":"Data Science and Advanced Analytics, St. Michael\u2019s Hospital, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"Reiskanen","sequence":"additional","affiliation":[{"name":"Translational Immunology Research 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