{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:23:06Z","timestamp":1783506186196,"version":"3.55.0"},"reference-count":60,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100009389","name":"Stiftelsen Promobilia","doi-asserted-by":"publisher","award":["20111"],"award-info":[{"award-number":["20111"]}],"id":[{"id":"10.13039\/100009389","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pain is a common symptom of multiple sclerosis (MS). The reliability of outcome measures for pain and the accuracy of screening tools are essential for treatment purposes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study investigated the test\u2013retest reliability of Neuropathic Pain Scale (NPS), Neuropathic Pain Symptom Inventory (NPSI), Brief Pain Inventory-Short Form (BPI-SF), Nordic Musculoskeletal Questionnaire (NMQ), Douleur Neuropathique 4 (DN4), and painDETECT, and the accuracy of DN4 and painDETECT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>110 persons with MS were included (mean age: 45.35 \u00b1 12.73; Expanded Disability Status Scale (EDSS): 3 (Interquartile range, IQR: 2.6)). The reliability (internal consistency, test\u2013retest, measurement error) and accuracy (area under the curve (AUC), specificity, sensitivity, positive predictive value, and negative predictive value) were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>All included pain assessment tools showed good test\u2013retest reliability (Intraclass correlation coefficient, ICC, (95% confidence interval, CI): 0.85 (0.79\u20130.89)\u20130.89 (0.84\u20130.92)) and good-to-excellent internal consistency (Cronbach\u2019s \u03b1: 0.73\u20130.93). The test\u2013retest reliability of NMQ was moderate to substantial (Cohen\u2019s \u03ba = 0.54\u20130.87). The overall accuracy of DN4 compared to the neurologist\u2019s diagnosis was acceptable (AUC = 0.762), while that of painDETECT was poor (AUC = 0.682) and demonstrated inadequate predictive ability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>All pain outcome measures were reliable in patients with MS (pwMS). DN4 can be used to screen neuropathic pain in MS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registry name:<\/jats:title>\n                    <jats:p>\n                      Reliability and Validity of Outcome Measures for Pain in MS\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/register.clinicaltrials.gov\/prs\/app\/action\/SelectProtocol?sid=S000CRMD&amp;selectaction=Edit&amp;uid=U0006NAA&amp;ts=2&amp;cx=-jzvd6m\">https:\/\/register.clinicaltrials.gov\/prs\/app\/action\/SelectProtocol?sid=S000CRMD&amp;selectaction=Edit&amp;uid=U0006NAA&amp;ts=2&amp;cx=-jzvd6m<\/jats:ext-link>\n                      Registration number: NCT05742152\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13524585241310139","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T02:14:31Z","timestamp":1737080071000},"page":"474-488","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessing pain in multiple sclerosis: Test\u2013retest reliability of patient-reported outcome measures and accuracy of screening tools"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9607-9662","authenticated-orcid":false,"given":"Cigdem","family":"Yilmazer","sequence":"first","affiliation":[{"name":"REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium"},{"name":"UMSC, Hasselt\/Pelt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"D\u2019haeseleer","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Brussels (UZ Brussel), Brussels, Belgium"},{"name":"National Multiple Sclerosis Center Melsbroek, Melsbroek, Belgium"},{"name":"Center for Neurosciences, Neuroprotection and Neuromodulation Research Group, Vrije Universiteit Brussel, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8143-4497","authenticated-orcid":false,"given":"Bernardita","family":"Soler","sequence":"additional","affiliation":[{"name":"Neurology, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"},{"name":"Neurology, Hospital S\u00f3tero del R\u00edo, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Van Wijmeersch","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium"},{"name":"UMSC, Hasselt\/Pelt, Belgium"},{"name":"Noorderhart Rehabilitation and MS Center, Pelt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Solaro","sequence":"additional","affiliation":[{"name":"CRRF \u201cMons. Luigi Novarese,\u201d Moncrivello, Italy"},{"name":"Neurology Unit, Galliera Hospital, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7330-5433","authenticated-orcid":false,"given":"Ethel","family":"Ciampi","sequence":"additional","affiliation":[{"name":"Neurology, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"},{"name":"Neurology, Hospital S\u00f3tero del R\u00edo, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Carcamo","sequence":"additional","affiliation":[{"name":"Neurology, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Van Asch","sequence":"additional","affiliation":[{"name":"Fit-Up Physiotherapy Center, Kontich, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Cambron","sequence":"additional","affiliation":[{"name":"Department of Neurology, AZ Sint-Jan Brugge, Brugge, Belgium"},{"name":"Ghent University, Ghent, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6147-4769","authenticated-orcid":false,"given":"Ilse","family":"Lamers","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium"},{"name":"UMSC, Hasselt\/Pelt, Belgium"},{"name":"Noorderhart Rehabilitation and MS Center, Pelt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5680-5495","authenticated-orcid":false,"given":"Peter","family":"Feys","sequence":"additional","affiliation":[{"name":"REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium"},{"name":"UMSC, Hasselt\/Pelt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.08.024"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.05.024"},{"key":"e_1_3_2_4_2","unstructured":"International Association for the Study of Pain. Terminology pain terms and definitions. https:\/\/www.iasp-pain.org\/resources\/terminology\/ (accessed November 2024)"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6579-2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.12.002"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2023.105401"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458520952015"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269215513514231"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.2.332"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2003.12.024"},{"key":"e_1_3_2_12_2","first-page":"143","article-title":"The brief pain inventory","volume":"20","author":"Cleeland CS","year":"1991","unstructured":"Cleeland CS, Ryan K. The brief pain inventory. Pain Res Group 1991; 20: 143\u2013147.","journal-title":"Pain Res Group"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S20309"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2015.1114034"},{"issue":"2","key":"e_1_3_2_15_2","first-page":"114","article-title":"A survey of severity and distribution of musculoskeletal pain in multiple sclerosis patients; a cross-sectional study","volume":"3","author":"ShayestehAzar M","year":"2015","unstructured":"ShayestehAzar M, Kariminasab MH, Saravi MS, et al. A survey of severity and distribution of musculoskeletal pain in multiple sclerosis patients; a cross-sectional study. Arch Bone Jt Surg 2015; 3(2): 114\u2013118.","journal-title":"Arch Bone Jt Surg"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00045.2019"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.12.010"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1185\/030079906X132488"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-68382-5_2"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000002793"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msksp.2017.05.010"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/papr.12671"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1498"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pnad165"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187961"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30470-2"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-6870(87)90010-X"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/135245859900500409"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1159\/000115178"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517690824"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/67.2.206"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2012-019"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517690821"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.2307\/2136404"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(89)90047-4"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.02.006"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-018-1829-0"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-017-1765-4"},{"key":"e_1_3_2_41_2","volume-title":"Research methods in psychology","author":"Price PC","year":"2017","unstructured":"Price PC, Jhangiani R, Chiang I, et al. Research methods in psychology. 3rd American ed. Washington, DC: Press Books Publications, 2017."},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.11613\/BM.2012.031"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.02.012"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2006.03.012"},{"issue":"1","key":"e_1_3_2_45_2","first-page":"231","article-title":"Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM","volume":"19","author":"Weir JP","year":"2005","unstructured":"Weir JP. Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. J Strength Cond Res 2005; 19(1): 231\u2013240.","journal-title":"J Strength Cond Res"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2005.10.015"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.4103\/picr.PICR_170_17"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.4103\/picr.PICR_41_18"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2002.10750.x"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118548387"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2015.03.010"},{"key":"e_1_3_2_52_2","first-page":"51","article-title":"Systematic review on the psychometric, reliability and validity properties of translated neuropathic pain screening tools (DN4, LANSS and PDQ) 1 January 2005\u201319 July 2019","volume":"7","author":"Fagbohun T","year":"2021","unstructured":"Fagbohun T. Systematic review on the psychometric, reliability and validity properties of translated neuropathic pain screening tools (DN4, LANSS and PDQ) 1 January 2005\u201319 July 2019. Int J Med Res 2021; 7: 51\u201367.","journal-title":"Int J Med Res"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41393-019-0338-5"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e31805d0c5d"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2006.03.008"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2005.10.007"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2011.03500.x"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000492"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.11.019"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2017.30.1.51"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12222"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13524585241310139","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/13524585241310139","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13524585241310139","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:17:15Z","timestamp":1777695435000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/13524585241310139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,16]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/13524585241310139"],"URL":"https:\/\/doi.org\/10.1177\/13524585241310139","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,16]]}}}