{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:38:15Z","timestamp":1777937895091,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000261","name":"Multiple Sclerosis Society of Canada","doi-asserted-by":"publisher","award":["EGID 903015"],"award-info":[{"award-number":["EGID 903015"]}],"id":[{"id":"10.13039\/501100000261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Mothers with MS face an increased incidence and prevalence of peripartum mental illness as compared to mothers without MS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To determine the factors associated with the risk of peripartum mental illness among mothers with MS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We identified mothers with MS with live births between 2002 and 2019 using linked population-based administrative data from Ontario, Canada. Using validated definitions, we estimated the incidence of mental illness (depression, anxiety, bipolar disorder) from conception through the first post-partum year (peripartum period). We used multivariable Poisson regression to assess the association between age, delivery year, area-level deprivation (Ontario Marginalization Index), disease duration, disability, and comorbidity and incidence of peripartum mental illness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 1745 mothers with MS, the mean (SD) age at conception was 31.2 (4.8) years. Mothers living in communities that lacked cohesion had increased rates of peripartum depression (incidence rate ratio [IRR] 1.25; 1.11\u20131.42) and anxiety (IRR 1.20; 1.07\u20131.33). Elevated MS disability level was associated with elevated peripartum depression rates (IRR 1.51; 1.12\u20132.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Higher area-level deprivation and disability levels are associated with an increased incidence of peripartum mental illness. These findings may assist clinicians in identifying women with MS who may benefit from peripartum mental health support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13524585251330109","type":"journal-article","created":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T07:03:03Z","timestamp":1745046183000},"page":"846-855","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk factors for incident peripartum mental illness in multiple sclerosis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1855-5595","authenticated-orcid":false,"given":"Ruth Ann","family":"Marrie","sequence":"first","affiliation":[{"name":"Department of Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M","family":"Bolton","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicki","family":"Ling","sequence":"additional","affiliation":[{"name":"ICES Central, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles N","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0090-597X","authenticated-orcid":false,"given":"Kristen M","family":"Krysko","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology), St. Michael\u2019s Hospital, University of Toronto, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[{"name":"ICES Central, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyla A","family":"McKay","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda","family":"Razaz","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7280-3684","authenticated-orcid":false,"given":"Dalia L","family":"Rotstein","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology), St. Michael\u2019s Hospital, University of Toronto, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karma","family":"Deakin-Harb","sequence":"additional","affiliation":[{"name":"Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen","family":"Maxwell","sequence":"additional","affiliation":[{"name":"ICES Central, Toronto, ON, Canada"},{"name":"School of Pharmacy, University of Waterloo, Waterloo, ON, Canada"},{"name":"School of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,4,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002174"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2017.07.015"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000012062"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458516631037"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000210170"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0177065"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2018.2132"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.20865"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/0884217504270666"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2015.11.014"},{"key":"e_1_3_3_12_2","unstructured":"Statistics Canada. Ontario [Province] and Canada [Country] (Table). Census Profile 2016 Census. Statistics Canada Catalogue no. 98-316-X2016001 https:\/\/www12.statcan.gc.ca\/census-recensement\/2016\/dp-pd\/prof\/details\/Page.cfm?Lang=E&Geo1=PR&Code1=35&Geo2=&Code2=&Data=Count&SearchText=Ontario&Sear (2017 accessed 28 August 2021)."},{"key":"e_1_3_3_13_2","volume-title":"Canadian Institute for Health Information discharge abstract database: A validation study","author":"Juurlink D","year":"2006","unstructured":"Juurlink D, Preyra C, Croxford R, et al. Canadian Institute for Health Information discharge abstract database: A validation study. Toronto, ON, Canada: Institute for Clinical Evaluative Sciences, 2006."},{"key":"e_1_3_3_14_2","volume-title":"Ontario mental health reporting system metadata","author":"Canadian Institute for Health Information","year":"2024","unstructured":"Canadian Institute for Health Information. Ontario mental health reporting system metadata. Toronto, ON, Canada: Canadian Institute for Health Information, 2024."},{"key":"e_1_3_3_15_2","volume-title":"Perinatal data at ICES","author":"Park A","year":"2020","unstructured":"Park A. Perinatal data at ICES. Toronto, ON, Canada: ICES, 2020."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2017.301"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796017000579"},{"key":"e_1_3_3_18_2","volume-title":"2021 Ontario Marginalization Index","author":"Matheson F","year":"2021","unstructured":"Matheson F, Moloney G, Van Ingen T. 2021 Ontario Marginalization Index. 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