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Follow-up revealed a resolution of symptoms and lesion enhancement. The total duration of lesion enhancement was 14 months. Recognizing the possibility of long-lasting enhancement in AQP4-positive myelitis is crucial for diagnostic accuracy. Moreover, it may indicate subclinical disease activity, and might suggest the need for close magnetic resonance imaging (MRI) monitoring and an adjustment in therapeutic strategy.<\/jats:p>","DOI":"10.1177\/13524585251352315","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T02:23:22Z","timestamp":1751855002000},"page":"1385-1389","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Long-standing gadolinium enhancement in a patient with aquaporin-4-positive myelitis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2376-6393","authenticated-orcid":false,"given":"Ali\u00e9nor","family":"Jaillard","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, Piti\u00e9-Salp\u00eatri\u00e8re University Hospital, Assistance Publique Hopitaux de Paris-Sorbonne University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7699-0328","authenticated-orcid":false,"given":"Elisabeth","family":"Maillart","sequence":"additional","affiliation":[{"name":"Department of Neurology, MS Resource and Competence Center, Piti\u00e9-Salp\u00eatri\u00e8re University Hospital, Assistance Publique Hopitaux de Paris-Sorbonne University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Shor","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Piti\u00e9-Salp\u00eatri\u00e8re University Hospital, Assistance Publique Hopitaux de Paris-Sorbonne University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001729"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11910-z"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2021.577702"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11634-0"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410340507"},{"key":"e_1_3_2_7_2","article-title":"More efficient complement activation by anti\u2013aquaporin-4 compared with anti\u2013myelin oligodendrocyte glycoprotein antibodies","volume":"10","author":"Lerch M","year":"2022","unstructured":"Lerch M, Schanda K, Lafon E, et al. 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