{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:39:08Z","timestamp":1777937948549,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:00:00Z","timestamp":1751846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:00:00Z","timestamp":1751846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100007324","name":"Sundhedsstyrelsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007324","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The relationship between attendance at specialized multiple sclerosis (MS) clinics and mortality has not been fully evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>We investigated the association between visits to specialized care in Danish MS clinics and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We collected data from Danish national registers to assess survival among people with MS according to the number of visits in MS clinics. We employed the Kaplan\u2013Meier method and extended Cox regression modelling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In total, 9929 patients with MS were included in the study, contributing 105 115 person-years at risk. A total of 316 patients with MS died during a median follow-up of 10.3 years. Cumulative visits were not statistically associated with mortality (hazard ratio (HR), 95% confidence interval (CI) = 1.00, 0.99\u20131.02). Female sex (0.68, 0.53\u20130.87), being divorced (0.56, 0.37\u20130.86), being married or in a partnership (0.60, 0.45\u20130.79) and higher education (0.64, 0.45\u20130.91) were independently associated with reduced mortality. Expanded Disability Status Scale (EDSS) \u2a7e 3 (2.38, 1.60\u20133.54), ischaemic cerebrovascular disease (1.97, 1.42\u20132.75) and pneumonia (7.03, 5.48\u20139.02) were associated with an increased mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We found no association between visits to specialized care and mortality. Our findings suggest that improving survival in patients with MS may require a focus on quality and content of care and proactive management of comorbidities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13524585251353079","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T05:03:50Z","timestamp":1751864630000},"page":"1294-1303","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the association between mortality and clinical follow-up visits in multiple sclerosis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1191-7300","authenticated-orcid":false,"given":"Agata","family":"Beczek","sequence":"first","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eskild Morten","family":"Landt","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Zealand University Hospital, K\u00f8ge, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda","family":"Magyari","sequence":"additional","affiliation":[{"name":"Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen, Denmark"},{"name":"University Hospital\u2013Rigshospitalet, Glostrup, Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars Kristian","family":"Storr","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6686-312X","authenticated-orcid":false,"given":"Morten","family":"Dahl","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Zealand University Hospital, K\u00f8ge, Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000535960"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11111551"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/ane.13559"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.0664"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2016-067"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000269"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-023-03021-3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-021-07138-0"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2022.0496"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2006.00626.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-0081"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12654"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458514564491"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000209135"},{"key":"e_1_3_3_16_2","article-title":"The Danish multiple sclerosis registry","volume":"11","author":"Magyari M","year":"2020","unstructured":"Magyari M, Joensen H, Laursen B, et al. The Danish multiple sclerosis registry. Brain Behav 2020; 11: e01921.","journal-title":"Brain Behav"},{"key":"e_1_3_3_17_2","unstructured":"Danmarks Statistik. Statistics Denmark https:\/\/www.dst.dk\/en\/OmDS (accessed 5 November 2024)."},{"key":"e_1_3_3_18_2","unstructured":"SUNDHEDSDATA-STYRELSEN. The Danish Health Data Authority https:\/\/sundhedsdatastyrelsen.dk\/da\/english\/health_data_and_registers\/national_health_registers\/list-of-national-health-registers (accessed 5 November 2024)."},{"key":"e_1_3_3_19_2","unstructured":"Danish Research Ethics Committee. Health Research Ethics https:\/\/researchethics.dk\/about-the-danish-research-ethics-committee-system (accessed 5 November 2024)."},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_3_3_21_2","unstructured":"Datatilsynet. Danish data protection legislation https:\/\/www.datatilsynet.dk\/english\/legislation (accessed 5 November 2024)."},{"issue":"3","key":"e_1_3_3_22_2","article-title":"Prioritizing the healthcare access concerns of Canadians with MS.","volume":"7","author":"P\u00e9trin J","year":"2021","unstructured":"P\u00e9trin J, McColl MA, Donnelly C, et al. Prioritizing the healthcare access concerns of Canadians with MS. Mult Scler J Exp Transl Clin 2021; 7(3): 20552173211029672.","journal-title":"Mult Scler J Exp Transl Clin"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2015.07.008"},{"issue":"2","key":"e_1_3_3_24_2","article-title":"Mortality of multiple sclerosis in Iceland population-based mortality of MS in incidence and prevalence cohorts","volume":"9","author":"Eliasdottir O","year":"2023","unstructured":"Eliasdottir O, Kjartansson \u00d3, Olafsson E. 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