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Temporal lobe-limbic encephalitis was the most common HSV infection (13 patients), followed by meningitis (5), diffuse encephalitis (4), disseminated encephalomyelitis (ADEM) (3) and brain stem encephalitis (2). Another three patients with non-herpetic, non-paraneoplastic acute limbic encephalitis were presented. Our study indicates that HSV infection can cause ADEM, although temporal lobe-limbic encephalitis or meningitis are more common. The early diagnosis of HSV-related ADEM is important because of the efficacy of the timely administration of corticosteroids.<\/jats:p>","DOI":"10.1177\/135245859600200204","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T22:19:25Z","timestamp":1484691565000},"page":"83-87","source":"Crossref","is-referenced-by-count":26,"title":["Survey of herpes simplex virus infections of the central nervous system, including acute disseminated encephalomyelitis, in the Kyushu and Okinawa regions of Japan"],"prefix":"10.1177","volume":"2","author":[{"given":"M","family":"Kaji","sequence":"first","affiliation":[{"name":"First Department (Neurology) of Internal Medicine, Kurume University School of Medicine, Asahimachi 67, Kurume, 830 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Kusuhara","sequence":"additional","affiliation":[{"name":"First Department (Neurology) of Internal Medicine, Kurume University School of Medicine, 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